Epigenome-wide association study identifies novel genes associated with ischemic stroke

被引:0
作者
Hao Peng
Helena Palma-Gudiel
Carolina Soriano-Tarraga
Jordi Jimenez-Conde
Mingzhi Zhang
Yonghong Zhang
Jinying Zhao
机构
[1] Medical College of Soochow University,Department of Epidemiology, School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases
[2] University of Florida,Department of Epidemiology, College of Public Health and Health Professions and College of Medicine
[3] Universitat Autònoma de Barcelona/DCEXS,Neurovascular Research Group, Department of Neurology of Hospital del Mar
[4] Universitat Pompeu Fabra,IMIM (Institut Hospital del Mar d’Investigacions Mèdiques)
[5] Washington University School of Medicine,Department of Psychiatry
[6] Washington University School of Medicine,Hope Center for Neurological Disorders
[7] Washington University in St. Louis,NeuroGenomics and Informatics, Department of Psychiatry
来源
Clinical Epigenetics | / 15卷
关键词
DNA methylation; Ischemic stroke; EWAS; CRISPR/dCas9-Dnmt3a; Chinese population;
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  • [1] Li Z(2019)China’s response to the rising stroke burden BMJ 364 e153-e639
  • [2] Jiang Y(2022)Heart disease and stroke statistics-2022 update: a report from the American Heart Association Circulation 145 761-775
  • [3] Li H(2016)Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study Lancet 388 3161-3167
  • [4] Tsao CW(2012)Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations Stroke 43 524-537
  • [5] Aday AW(2018)Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes Nat Genet 50 7663-7677
  • [6] Almarzooq ZI(2019)Association between promoter DNA methylation and gene expression in the pathogenesis of ischemic stroke Aging (Albany, NY). 11 1330-1338
  • [7] O’Donnell MJ(2019)Epigenome-wide association study indicates hypomethylation of MTRNR2L8 in large-artery atherosclerosis stroke Stroke 50 988-997
  • [8] Chin SL(2020)Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study Epigenetics 15 479-489
  • [9] Rangarajan S(2021)DNA methylation analyses identify an intronic ZDHHC6 locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial PLoS ONE 16 250-253
  • [10] Bevan S(2020)The role of DNA methylation in ischemic stroke: a systematic review Front Neurol 11 257LP-262