Influence of enzymatic reactions on blood coagulation autowave

被引:0
作者
Pogorelova E.A. [1 ,2 ]
Lobanov A.I. [1 ,3 ]
机构
[1] Moscow Institute of Physics and Technology (State University), Dolgoprudny, Moscow Region
[2] Center for Theoretical Problems of Physicochemical Biology, Russian Academy of Sciences, Moscow
[3] Moscow State Academy of Water Transport, Moscow
关键词
reaction-diffusion; autowave; blood coagulation; blood-coagulation factors;
D O I
10.1134/S0006350914010151
中图分类号
学科分类号
摘要
A model of blood coagulation has been investigated. The model includes 25 "reaction-diffusion" equations describing the space-time dynamics of distribution of blood coagulation factor concentrations. The one-dimensional statement of the problem is considered. The autowave velocity has been estimated based on the spatial distribution of blood coagulation factors obtained by numerical calculation of the problem. The dependence of the autowave velocity on diffusion coefficients of prothrombin, AT-III, thrombin, and thrombin bound to α2-macroglobulin is estimated. © 2014 Pleiades Publishing, Inc.
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页码:110 / 118
页数:8
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