Combined effects of a high-fat diet and chronic valproic acid treatment on hepatic steatosis and hepatotoxicity in rats

被引:0
|
作者
Li-fang Zhang
Ling-sheng Liu
Xiao-man Chu
Hao Xie
Li-juan Cao
Cen Guo
Ji-ye A
Bei Cao
Meng-jie Li
Guang-ji Wang
Hai-ping Hao
机构
[1] State Key Laboratory of Natural Medicines,Department of Clinical Pharmacology
[2] Key Laboratory of Drug Metabolism and Pharmacokinetics,undefined
[3] China Pharmaceutical University,undefined
[4] Jinling Hospital,undefined
来源
Acta Pharmacologica Sinica | 2014年 / 35卷
关键词
valproic acid; high-fat diet; drug diet interaction; non-alcoholic fatty liver disease; hepatotoxicity; tricarboxylic acid cycle; amino acid; free fatty acid; metabonomics;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:363 / 372
页数:9
相关论文
共 50 条
  • [31] Inhibitory effects of Rubi Fructus extracts on hepatic steatosis development in high-fat diet-induced obese mice
    Nam, Mi Kyung
    Choi, Hye Ran
    Cho, Jin Sook
    Cho, Soo Min
    Ha, Ki Chan
    Kim, Tae-Hyeon
    Ryu, Hee-Young
    Lee, Young-Ik
    MOLECULAR MEDICINE REPORTS, 2014, 10 (04) : 1821 - 1827
  • [32] Piperine attenuates hepatic steatosis and insulin resistance in high-fat diet-induced obesity in Sprague-Dawley rats
    Wang, Xiong
    Zhang, Yanhua
    Zhang, Lei
    Wang, Wenli
    Che, Huilian
    Zhang, Yali
    NUTRITION RESEARCH, 2022, 108 : 9 - 21
  • [33] Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats
    Xia, Hong-Miao
    Wang, Jin
    Xie, Xiao-Jie
    Xu, Li-Juan
    Tang, Shi-Qi
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019, 44 (04) : 1523 - 1530
  • [34] Hepatic biochemical changes in rats submitted to a high-fat/high-energy diet
    de Moura, Leandro Pereira
    Dalia, Rodrigo Augusto
    de Araujo, Michel Barbosa
    da Silva Sponton, Amanda Christine
    Pauli, Jose Rodrigo
    de Moura, Rodrigo Ferreira
    Rostom de Mello, Maria Alice
    REVISTA DE NUTRICAO-BRAZILIAN JOURNAL OF NUTRITION, 2012, 25 (06): : 685 - 693
  • [35] Investigating the Hepatic Response to Orlistat and White Tea in Rats on a High-Fat Diet
    Ciftel, Serpil
    Klisic, Aleksandra
    Ciftel, Enver
    Mercantepe, Tolga
    Yilmaz, Adnan
    Ciftel, Sedat
    Pinarbas, Esra
    Toraman, Merve Nur
    Mercantepe, Filiz
    LIFE-BASEL, 2024, 14 (10):
  • [36] High-fat diet effect on periapical lesions and hepatic enzymatic antioxidant in rats
    Tiburcio-Machado, Camilla dos Santos
    Lang, Pauline Mastella
    Campos, Maria Martha
    Brilhante Wolle, Carlos Frederico
    Silva Barcelos, Raquel Cristine
    Zago, Natalia Brezolin
    Leite, Carlos Eduardo
    Etges, Adriana
    Souza Bier, Carlos Alexandre
    LIFE SCIENCES, 2021, 264
  • [37] Protective effects of naringin on valproic acid-induced hepatotoxicity in rats
    Koroglu, Omer Faruk
    Gunata, Mehmet
    Vardi, Nigar
    Yildiz, Azibe
    Ates, Burhan
    Colak, Cemil
    Tanriverdi, Lokman Hekim
    Parlakpinar, Hakan
    TISSUE & CELL, 2021, 72
  • [38] High-fat diet overfeeding promotes nondetrimental liver steatosis in female mice
    Arisqueta, Lino
    Navarro-Imaz, Hiart
    Labiano, Ibone
    Rueda, Yuri
    Fresnedo, Olatz
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2018, 315 (05): : G772 - G780
  • [39] Bardoxolone methyl prevents insulin resistance and the development of hepatic steatosis in mice fed a high-fat diet
    Camer, Danielle
    Yu, Yinghua
    Szabo, Alexander
    Dinh, Chi H. L.
    Wang, Hongqin
    Cheng, Licai
    Huang, Xu-Feng
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2015, 412 (0C) : 36 - 43
  • [40] Mentha canadensis attenuates adiposity and hepatic steatosis in high-fat diet-induced obese mice
    Han, Youngji
    Choi, Ji-Young
    Kwon, Eun-Young
    NUTRITION RESEARCH AND PRACTICE, 2023, 17 (05) : 870 - 882