Influence of Melatonin-Correcting Drugs (Melaxen and Valdoxan) on the Levels of Superoxide Dismutase and Catalase Gene Transcription in Rats with Experimental Hyperthyroidism

被引:0
|
作者
T. N. Popova
A. A. Agarkov
M. V. Gorbenko
S. S. Popov
K. K. Shul’gin
机构
[1] Voronezh State University,
[2] N. N. Burdenko Voronezh State Medical Academy,undefined
来源
Pharmaceutical Chemistry Journal | 2016年 / 50卷
关键词
gene-transcription level; melaxen; Valdoxan; superoxide dismutase; catalase;
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学科分类号
摘要
The influence of the melatonin-correcting drugs melaxen and Valdoxan on the gene-transcription level of superoxide dismutase (SOD, EC 1.15.1.1) and catalase (EC 1.11.1.6) in liver and heart of rats with hyperthyroidism has been investigated. Administration of these drugs to rats with model pathology leads to changes in SOD and catalase expression in their tissues toward the control values.
引用
收藏
页码:127 / 130
页数:3
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  • [1] Influence of Melatonin-Correcting Drugs (Melaxen and Valdoxan) on the Levels of Superoxide Dismutase and Catalase Gene Transcription in Rats with Experimental Hyperthyroidism
    Popova, T. N.
    Agarkov, A. A.
    Gorbenko, M. V.
    Popov, S. S.
    Shul'gin, K. K.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2016, 50 (03) : 127 - 130
  • [2] Effects of Melaxen and Valdoxan on Superoxide Dismutase and Catalase Activities in Experimental Hyperthyroidism
    M. V. Gorbenko
    T. N. Popova
    K. K. Shul’gin
    S. S. Popov
    Pharmaceutical Chemistry Journal, 2014, 47 : 577 - 580
  • [3] Effects of Melaxen and Valdoxan on Superoxide Dismutase and Catalase Activities in Experimental Hyperthyroidism
    Gorbenko, M. V.
    Popova, T. N.
    Shul'gin, K. K.
    Popov, S. S.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2014, 47 (11) : 577 - 580