Clinical evidence for immunomodulation induced by high-dose melphalan and autologous blood stem cell transplantation as cause for complete clinical remission of multiple myeloma-associated cryoglobulin-vasculitis

被引：0
|
作者：
J. Hillengass
A. D. Ho
H. Goldschmidt
R. Waldherr
T. M. Moehler
机构：
[1] University Hospital of Heidelberg,Department of Hematology, Oncology and Rheumatology
[2] Gemeinschaftspraxis Pathologie,undefined
来源：
International Journal of Hematology | 2008年 / 88卷
关键词：
Cryoglobulinemia; Multiple myeloma; Stem cell transplantation; Immune reset;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We present a case report of a patient with cryoglobulin-vasculitis caused by multiple myeloma in Durie/Salmon stage I refractory to conventional therapy modalities treated with high-dose chemotherapy followed by autologous blood stem cell transplantation. While clinical symptoms of vasculitis disappeared, elevated cryoglobulin levels persisted. Therefore we conclude that the relief of symptoms was caused by an immunomodulation induced by the autologous stem cell transplantation.
引用
收藏
页码：454 / 456
页数：2
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