Synthesis, Two-Photon Absorption, and Cellular Imaging of Two Curcumin Derivatives

被引：0
作者：
W. Zhang
S. S. Zhou
G. F. Si
J. F. Wang
G. Y. Xu
机构：
[1] Anhui University of Chinese Medicine,Department of Pharmacy
[2] Anhui University,Center of Modern Experimental Technology
来源：
Russian Journal of General Chemistry | 2019年 / 89卷
关键词：
curcumin derivative; two-photon absorption; TPA cross-section; cellular imaging;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two curcumin derivatives, 1,7-bis(4-bromoethyloxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione (1) and 1,7-bis(4-bromobutyloxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione (2), have been conveniently synthesized and their structures characterized by 1H NMR and mass spectra, and single crystal X-ray diffraction measurements. Single-photon and two-photon fluorescence properties have been studied. The calculated two-photon absorption cross-sections for both compounds by quantum chemical method are as high as 358 and 326 GM, respectively. Two-photon fluorescent imaging of MCF-7 cells labeled with the compound 1 indicates its potential application as a biological fluorescent probe.
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页码：2577 / 2583
页数：6
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