Cell-based therapies in Parkinson’s disease

被引：0
|
作者：
Paul Greene
机构：
[1] Columbia University Medical Center,Department of Neurology
来源：
Current Neurology and Neuroscience Reports | 2009年 / 9卷
关键词：
Human Fetal Tissue; Human Neural Stem Cell; Troublesome Dyskinesia; Conserve Dopamine Neurotrophic Factor; Fetal Tissue Transplantation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The possibility of using stem cells to treat Parkinson’s disease has excited physicians and patients alike. However, after many encouraging open-label studies of fetal cell transplantation for Parkinson’s disease, three randomized, double-blind, placebo-controlled studies found no net benefit. In addition, patients in two of the studies developed dyskinesias that persisted despite reductions in medication. To realize the promise of stem cells, research has been undertaken to understand and overcome the dual problems of unpredictable benefit and troublesome dyskinesias after dopaminergic cell transplantation.
引用
收藏
页码：292 / 297
页数：5
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