Polyfunctional Pyrazoles. 8*. Synthesis of 6-Alkyl-2-Aryl-2H-Pyrazolo[4,3-d]Pyrimidine-5,7(4H,6H)-Diones based on Ethyl 1-Aryl-4-Isocyanatopyrazole-3-Carboxylates

被引：0

作者：

M. K. Bratenko

M. M. Barus

M. V. Vovk

机构：

[1] Bukovinsk State Medical University,Institute of Organic Chemistry

[2] National Academy of Sciences of Ukraine,undefined

来源：

Chemistry of Heterocyclic Compounds | 2013年 / 49卷

关键词：

6-alkyl-2-arylpyrazolo[4,3-; ]pyrimidine-5,7-diones; 1-aryl-3-ethoxycarbonylpyrazole-4-carboxylic acids; 1-aryl-4-ureidopyrazole-3-carboxylic acids; ethyl 1-aryl-4-formylpyrazole-3-carboxylates; ethyl 1-aryl-4-isocyanatopyrazole-3-carboxylates; intramolecular cyclization;

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学科分类号：

摘要：

A method for the preparation of 6-alkyl-2-aryl-2H-pyrazolo[4,3-d]pyrimidine-5,7(4H,6H)-diones in reaction of ethyl 1-aryl-4-isocyanatopyrazole-3-carboxylates with aliphatic amines followed by cyclization of the obtained 4-ureidopyrazole-3-carboxylic acid esters in the presence of bases is proposed.

引用

页码：1345 / 1351

页数：6