DocetaxelA Pharmacoeconomic Review of its Use in the Treatment of Metastatic Breast Cancer

被引:0
作者
Harriet M. Lamb
Lynda R. Wiseman
机构
[1] Adis International Limited,
来源
PharmacoEconomics | 1998年 / 14卷
关键词
Breast Cancer; Paclitaxel; Docetaxel; Adis International Limited; Metastatic Breast Cancer;
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学科分类号
摘要
Advanced breast cancer has a poor prognosis (median duration of survival about 2 years); thus, treatment options are largely palliative. Recent studies with the taxoids docetaxel and paclitaxel suggest that these agents are effective second- line therapy in patients with metastatic breast cancer. Objective response rates range from 30 to 57% with docetaxel monotherapy in clinical trials in patients with advanced disease who had failed to respond to previous therapy, and the median time to disease progression ranges from 17 to 20 weeks.
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页码:447 / 459
页数:12
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