It's all in the details: Methods in breast development and cancer

被引:2
作者
Bentires-Alj M. [1 ]
Clarke R.B. [3 ]
Jonkers J. [4 ]
Smalley M. [6 ]
Stein T. [7 ]
机构
[1] , Basel
[2] University of Manchester, Breast Biology Group School of Cancer and Imaging Sciences, Paterson Institute for Cancer Research, Wilmslow Road, Manchester
[3] Division of Molecular Biology (P2), Plesmanlaan 121, Amsterdam
[4] Breakthrough Breast Cancer Centre, Institute of Cancer Research, 237 Fulham Road, London
[5] University of Glasgow, Division of Cancer Sciences and Molecular Pathology, Section of Pathology and Gene Regulation, Western Infirmary, Glasgow
关键词
Mammary Gland; Cancer Stem Cell; Luminal Cell; Epidermal Stem Cell; Cancer Stem Cell Model;
D O I
10.1186/bcr2346
中图分类号
学科分类号
摘要
The inaugural European Network for Breast Development and Cancer (ENBDC) meeting on 'Methods in Mammary Gland Development and Cancer' was held in Weggis, Switzerland last April. The goal was to discuss the details of techniques used to study mammary gland biology and tumourigenesis. Highlights of this meeting included the use of four-colour fluorescence for protein co-localisation in tissue microarrays, genome analysis at single cell resolution, technical issues in the isolation of normal and tumour stem cells, and the use of mouse models and mammary gland transplantations to elucidate gene function in mammary development and to study drug resistance in breast cancer. © 2009 BioMed Central Ltd.
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