Neurodegenerative diseases

被引:26
作者
Reith, Wolfgang [1 ]
机构
[1] Univ Klinikum Saarlandes, Klin Diagnost & Intervent Neuroradiol, Kirrberger Str, D-66424 Homburg, Germany
来源
RADIOLOGE | 2018年 / 58卷 / 03期
关键词
Alzheimer disease; Parkinson disease; Dementia; vascular; Hydrocephalus; normal pressure; Huntington disease; MILD COGNITIVE IMPAIRMENT; ALZHEIMERS-DISEASE; LEWY BODIES; PARKINSONS-DISEASE; DEMENTIA; DIAGNOSIS; PREVALENCE; BIOMARKERS; CRITERIA; PET;
D O I
10.1007/s00117-018-0363-y
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Neurodegenerative diseases are sporadic and rare hereditary disorders of the central nervous system, which cause a slowly progressive loss of function of specific neuron populations and their connections. Severe impairments and care dependency can be the sequelae. Neurodegenerative disorders are diseases of older people; therefore, the demographic shift leads to an increase in the number of affected patients. Radiologists will also become more involved. For this reason important neurodegenerative diseases are presented in this article. In addition to Alzheimer's and Parkinson's diseases these also include frontotemporal lobar degeneration, Lewy body dementia, vascular dementia, Creutzfeldt-Jakob disease and Huntington's chorea. The clinical symptoms and diagnostics are described, whereby the focus lies on typical results of morphological imaging.
引用
收藏
页码:241 / 258
页数:18
相关论文
共 48 条
[21]   MR-based in vivo hippocampal volumetrics:: 1.: Review of methodologies currently employed [J].
Geuze, E ;
Vermetten, E ;
Bremner, JD .
MOLECULAR PSYCHIATRY, 2005, 10 (02) :147-159
[22]   Cerebral microbleeds: a guide to detection and interpretation [J].
Greenberg, Steven M. ;
Vernooij, Meike W. ;
Cordonnier, Charlotte ;
Viswanathan, Anand ;
Salman, Rustorn Al-Shahi ;
Warach, Steven ;
Launer, Lenore J. ;
Van Buchem, Mark A. ;
Breteler, Monique M. B. .
LANCET NEUROLOGY, 2009, 8 (02) :165-174
[23]   Positron emission tomography imaging in dementia [J].
Herholz, K. ;
Carter, S. F. ;
Jones, M. .
BRITISH JOURNAL OF RADIOLOGY, 2007, 80 :S160-S167
[24]   Risk and incidence of dementia in a cohort of older subjects with Parkinson's disease in the United Kingdom [J].
Hobson, P ;
Meara, J .
MOVEMENT DISORDERS, 2004, 19 (09) :1043-1049
[25]   Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: a cross-sectional study [J].
Jack, Clifford R., Jr. ;
Wiste', Heathen J. ;
Weigand, Stephen D. ;
Rocca, Walter A. ;
Knopman, David S. ;
Mielke, Michelle M. ;
Lowe, Val J. ;
Senjem, Matthew L. ;
Gunter, Jeffrey L. ;
Preboske, Gregory M. ;
Pankratz, Vernon S. ;
Vemuri, Prashanthi ;
Petersen, Ronald C. .
LANCET NEUROLOGY, 2014, 13 (10) :997-1005
[26]   Neuropathological evaluation of mixed dementia [J].
Jellinger, K. A. ;
Attems, J. .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2007, 257 (1-2) :80-87
[27]   Current Therapeutic Options for Huntington's Disease: Good Clinical Practice Versus Evidence-Based Approaches? [J].
Killoran, Annie ;
Biglan, Kevin M. .
MOVEMENT DISORDERS, 2014, 29 (11) :1404-1413
[28]   Prevalence of superficial siderosis in patients with cerebral amyloid angiopathy [J].
Linn, J. ;
Halpin, A. ;
Demaerel, P. ;
Ruhland, J. ;
Giese, A. D. ;
Dichgans, M. ;
van Buchem, M. A. ;
Bruckmann, H. ;
Greenberg, S. M. .
NEUROLOGY, 2010, 74 (17) :1346-1350
[29]   Failure of endoscopic third ventriculostomy in the treatment of idiopathic normal pressure hydrocephalus [J].
Longatti, PL ;
Fiorindi, A ;
Martinuzzi, A .
MINIMALLY INVASIVE NEUROSURGERY, 2004, 47 (06) :342-345
[30]   Lewy body compared with Alzheimer dementia is associated with decreased functional connectivity in resting state networks [J].
Lowther, Eva R. ;
O'Brien, John T. ;
Firbank, Michael J. ;
Blamire, Andrew M. .
PSYCHIATRY RESEARCH-NEUROIMAGING, 2014, 223 (03) :192-201