The ability to provide information about variants in genes is crucial to genome-wide association studies. This article argues that the currently available marker sets are unlikely to provide adequate coverage of genic variants, and suggests how this problem could be overcome.
机构:
Univ Milan, Angelo Bianchi Bonomi Hemophilia & Thrombosis Ctr, Mangiagalli & Regina Elena Fdn,Luigi Villa Fdn, IRCCS,Maggiore Hosp,Dept Med & Med Special, I-20122 Milan, ItalyUniv Milan, Angelo Bianchi Bonomi Hemophilia & Thrombosis Ctr, Mangiagalli & Regina Elena Fdn,Luigi Villa Fdn, IRCCS,Maggiore Hosp,Dept Med & Med Special, I-20122 Milan, Italy