A gene-centric approach to genome-wide association studies

被引:0
|
作者
Eric Jorgenson
John S. Witte
机构
[1] University of California,Department of Epidemiology and Biostatistics, and Center for Human Genetics
来源
Nature Reviews Genetics | 2006年 / 7卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The ability to provide information about variants in genes is crucial to genome-wide association studies. This article argues that the currently available marker sets are unlikely to provide adequate coverage of genic variants, and suggests how this problem could be overcome.
引用
收藏
页码:885 / 891
页数:6
相关论文
共 50 条
  • [41] Genome-Wide Association Studies and Diet
    Ferguson, Lynnette R.
    JOURNAL OF NUTRIGENETICS AND NUTRIGENOMICS, 2010, 3 (4-6) : 144 - 150
  • [42] Replication in Genome-Wide Association Studies
    Kraft, Peter
    Zeggini, Eleftheria
    Ioannidis, John P. A.
    STATISTICAL SCIENCE, 2009, 24 (04) : 561 - 573
  • [43] A new gene-based association test for genome-wide association studies
    Alfonso Buil
    Angel Martinez-Perez
    Alexandre Perera-Lluna
    Leonor Rib
    Pere Caminal
    Jose Manuel Soria
    BMC Proceedings, 3 (Suppl 7)
  • [44] The road to genome-wide association studies
    Kruglyak, Leonid
    NATURE REVIEWS GENETICS, 2008, 9 (04) : 314 - 318
  • [45] Genome-wide association studies in ADHD
    Barbara Franke
    Benjamin M. Neale
    Stephen V. Faraone
    Human Genetics, 2009, 126 : 13 - 50
  • [46] Genome-Wide Association Studies of Cancer
    Stadler, Zsofia K.
    Thom, Peter
    Robson, Mark E.
    Weitzel, Jeffrey N.
    Kauff, Noah D.
    Hurley, Karen E.
    Devlin, Vincent
    Gold, Bert
    Klein, Robert J.
    Offit, Kenneth
    JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (27) : 4255 - 4267
  • [47] Genome-wide association studies in pharmacogenomics
    Daly, Ann K.
    NATURE REVIEWS GENETICS, 2010, 11 (04) : 241 - 246
  • [48] Genome-Wide Association Studies in Atherosclerosis
    S. Sivapalaratnam
    M. M. Motazacker
    S. Maiwald
    G. K. Hovingh
    J. J. P. Kastelein
    M. Levi
    M. D. Trip
    G. M. Dallinga-Thie
    Current Atherosclerosis Reports, 2011, 13 : 225 - 232
  • [49] The road to genome-wide association studies
    Leonid Kruglyak
    Nature Reviews Genetics, 2008, 9 : 314 - 318
  • [50] Genome-wide association studies in atherothrombosis
    Lotta, Luca Andrea
    EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2010, 21 (02) : 74 - 78