共 388 条
[31]
Garcia-Echeverria C(2003)Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation J Biol Chem 278 30458-2467
[32]
Shyr Y(2007)The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo Mol Cancer Ther 6 2458-1508
[33]
Arteaga CL(2006)mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt Cancer Res 66 1500-1160
[34]
Pancholi S(2002)PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest Nat Med 8 1153-6369
[35]
Lykkesfeldt AE(2009)S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation J Biol Chem 284 6361-233
[36]
Hilmi C(2008)Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy resistance Endocr Rev 29 217-562
[37]
Banerjee S(2009)Targeting PI3K signalling in cancer: opportunities, challenges and limitations Nat Rev Cancer 9 550-258
[38]
Leary A(2001)mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer Endocr Relat Cancer 8 249-2746
[39]
Drury S(2004)AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression J Biol Chem 279 2737-5328
[40]
Johnston S(2005)Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer Clin Cancer Res 11 5319-44