Synthesis of 1,5-Disubstituted 3-(4-Hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-pyrazolines

被引:0
作者
Albert Lévai
József Jekő
机构
[1] University of Debrecen,Department of Organic Chemistry
[2] ICN Hungary Co. Ltd.,undefined
来源
Monatshefte für Chemie / Chemical Monthly | 2006年 / 137卷
关键词
Keywords. α,β-Unsaturated ketones; Hydrazine; 2-Pyrazolines.;
D O I
暂无
中图分类号
学科分类号
摘要
A series of 1,5-disubstituted 3-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-pyrazolines were synthesized by the reaction of α,β-unsaturated ketones derived from dehydroacetic acid and hydrazine in hot acetic acid or propionic acid. The structures of all new compounds were elucidated by microanalyses, 1H and 13C NMR, IR, and mass spectroscopic measurements.
引用
收藏
页码:339 / 345
页数:6
相关论文
共 50 条
[31]   One-pot synthesis of substituted pyrrolo[3,4-b]pyridine-4,5-diones based on the reaction of N-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-oxo-2-arylethyl)acetamide with amines [J].
Melekhina, Valeriya G. ;
Komogortsev, Andrey N. ;
Lichitsky, Boris, V ;
Mityanov, Vitaly S. ;
Fakhrutdinov, Artem N. ;
Dudinov, Arkady A. ;
Migulin, Vasily A. ;
Nelyubina, Yulia, V ;
Melnikova, Elizaveta K. ;
Krayushkin, Michail M. .
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2019, 15 :2840-2846
[32]   4-Hydroxy-3-[(4-hydroxy-6,7-dimethyl-2-oxo-2H-chromen-3-yl)(4-oxo-4H-chromen-3-yl)methyl]-6,7-dimethyl-2H-chromen-2-one [J].
Asad, Mohammad ;
Oo, Chuan-Wei ;
Osman, Hasnah ;
Yeap, Chin Sing ;
Fun, Hoong-Kun .
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 :O2859-U571
[33]   Methyl 4-(7-diethylamino-2-oxo-2H-1-benzo-pyran-3-yl)benzoate [J].
Takechi, Haruko ;
Kubo, Kanji ;
Takahashi, Hajime ;
Matsumoto, Taisuke .
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 :O3826-O3828
[34]   SYNTHESIS OF 1-ACETYL-5-ARYL-3-[O-(3-CHLORO-2-INDOL-3-YL-4-OXO-1-AZETIDINYL)PHENYL]-2-PYRAZOLINES [J].
KUMAR, A ;
SINHA, JN ;
BHARGAVA, KP ;
SHANKER, K .
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1984, 23 (06) :589-591
[35]   Synthesis of masked 2-amino-6-methyl-4-oxo-4H-pyran-3-carbaldehydes [J].
Denisenko, Alexander V. ;
Tverdokhlebov, Anton V. .
FRENCH-UKRAINIAN JOURNAL OF CHEMISTRY, 2018, 6 (01) :67-73
[36]   3-(4-Bromophenyl)-4-{[3-hydroxy-6-(hydroxymethyl)-4-oxo-4H-pyran-2-yl](m-tolyl)methyl}isoxazol-5(2H)-one [J].
Ryzhkova, Yuliya E. ;
Ryzhkov, Fedor, V ;
Elinson, Michail N. .
MOLBANK, 2020, 2020 (02)
[37]   Synthesis and evaluation of antimicrobial activity of new 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxamide derivatives [J].
Aytemir, MD ;
Erol, DD ;
Hider, RC ;
Özalp, M .
TURKISH JOURNAL OF CHEMISTRY, 2003, 27 (06) :757-764
[38]   INTERACTION OF 1,5-DISUBSTITUTED 3-METHYL-2-OXO-2,3-DIHYDRO-1H-IMIDAZOLE-4-CARBONITRILES WITH HYDROGEN SULFIDE [J].
Chumachenko, S. A. ;
Shablykin, O. V. ;
Rusanov, E. B. ;
Brovarets, V. S. .
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2011, 47 (07) :807-810
[39]   Multicomponent protocol for the synthesis of substituted methyl 3-(3-hydroxy-4-oxo-4H-chromen-2-yl)propanoates from 3-hydroxy-4H-chromen-4-one [J].
Komogortsev, Andrey N. ;
Melekhina, Valeriya G. ;
Lichitsky, Boris V. .
SYNTHETIC COMMUNICATIONS, 2022, 52 (16) :1664-1671
[40]   SYNTHESIS AND ORAL HYPOGLYCEMIC PROPERTIES OF 3-(1-OXO-3-HYDROXY-2-CYCLOHEXEN-2-YL)-4-OXO-4,5,6,7-TETRAHYDROINDOLES [J].
NAGARAJAN, K ;
SHENOY, SJ ;
TALWALKER, PK .
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1989, 28 (04) :326-332