Genome-wide association study identifies 74 loci associated with educational attainment

被引：0

作者：

Aysu Okbay

Jonathan P. Beauchamp

Mark Alan Fontana

James J. Lee

Tune H. Pers

Cornelius A. Rietveld

Patrick Turley

Guo-Bo Chen

Valur Emilsson

S. Fleur W. Meddens

Sven Oskarsson

Joseph K. Pickrell

Kevin Thom

Pascal Timshel

Ronald de Vlaming

Abdel Abdellaoui

Tarunveer S. Ahluwalia

Jonas Bacelis

Clemens Baumbach

Gyda Bjornsdottir

Johannes H. Brandsma

Maria Pina Concas

Jaime Derringer

Nicholas A. Furlotte

Tessel E. Galesloot

Giorgia Girotto

Richa Gupta

Leanne M. Hall

Sarah E. Harris

Edith Hofer

Momoko Horikoshi

Jennifer E. Huffman

Kadri Kaasik

Ioanna P. Kalafati

Robert Karlsson

Augustine Kong

Jari Lahti

Sven J. van der Lee

Christiaan deLeeuw

Penelope A. Lind

Karl-Oskar Lindgren

Tian Liu

Massimo Mangino

Jonathan Marten

Evelin Mihailov

Michael B. Miller

Peter J. van der Most

Christopher Oldmeadow

Antony Payton

Natalia Pervjakova

机构：

[1] Erasmus School of Economics,Department of Applied Economics

[2] Erasmus University,Department of Epidemiology

[3] Erasmus Medical Center,Department of Economics

[4] Erasmus University Rotterdam Institute for Behavior and Biology,Department of Psychology

[5] Harvard University,Department of Epidemiology Research

[6] Center for Economic and Social Research,Department of Complex Trait Genetics

[7] University of Southern California,Department of Government

[8] University of Minnesota Twin Cities,Department of Economics

[9] Division of Endocrinology and Center for Basic and Translational Obesity Research,Department of Systems Biology

[10] Program in Medical and Population Genetics,Department of Biological Psychology

[11] Broad Institute of MIT and Harvard,Department of Obstetrics and Gynecology

[12] The Novo Nordisk Foundation Center for Basic Metabolic Research,Department of Cell Biology

[13] Section of Metabolic Genetics,Department of Medical

[14] University of Copenhagen,Department of Public Health

[15] Faculty of Health and Medical Sciences,Department of Cardiovascular Sciences

[16] Statens Serum Institut,Department of Neurology

[17] Queensland Brain Institute,Department of Medical Epidemiology and Biostatistics

[18] The University of Queensland,Department of Twin Research and Genetic Epidemiology

[19] Icelandic Heart Association,Department of Epidemiology

[20] Faculty of Pharmaceutical Sciences,Department of Health

[21] University of Iceland,Department of Medical Genetics

[22] VU University,Department Of Health Sciences

[23] Center for Neurogenomics and Cognitive Research,Division of Cancer Epidemiology and Genetics

[24] Amsterdam Business School,Department of Cardiology

[25] University of Amsterdam,Divisions of Genetics and Rheumatology, Department of Medicine

[26] Uppsala University,Department of Neurological Sciences

[27] New York Genome Center,Department of Epidemiology

[28] New York University,Department of Gastroenterology and Hepatology

[29] Center for Biological Sequence Analysis,Department of Behavioral Sciences

[30] Technical University of Denmark,Department of Psychology

[31] VU University Amsterdam,Nuffield Department of Population Health

[32] COPSAC,Department of Genetics, Division of Statistical Genomics

[33] Copenhagen Prospective Studies on Asthma in Childhood,Department of Genomics

[34] Herlev and Gentofte Hospital,Department of Psychiatry

[35] University of Copenhagen,Division of Applied Health Sciences

[36] Steno Diabetes Center,Departments of Neurology & Psychiatry

[37] Institute of Clinical Sciences,Department of Genes and Environment

[38] Sahlgrenska Academy,Department of Genomics of Common Disease

[39] Research Unit of Molecular Epidemiology,Department of Clinical Physiology

[40] Helmholtz Zentrum München,Department of Clinical Physiology

[41] German Research Center for Environmental Health,Department of Psychiatry and Behavioral Sciences

[42] Institute of Epidemiology II,Department of Internal Medicine

[43] Helmholtz Zentrum München,Department of Medicine

[44] German Research Center for Environmental Health,Department of Psychiatry

[45] deCODE Genetics/Amgen Inc.,Department of Neurology

[46] Erasmus Medical Center Rotterdam,Department of Economics

[47] Istituto di Ricerca Genetica e Biomedica U.O.S. di Sassari,Department of Psychiatry and Behavioral Sciences

[48] National Research Council of Italy,Department of Psychiatry and Behavioral Neuroscience

[49] Psychology,Department of Cardiovascular Science

[50] University of Illinois,Department of Geriatrics

来源：

Nature | 2016年 / 533卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

A genome-wide association study in 293,723 individuals identifies 74 genetic variants associated with educational attainment, which, although only explaining a small proportion of the variation in educational attainment, highlights candidate genes and pathways for further study.

引用

页码：539 / 542

页数：3

共 50 条

[1] Genome-wide association study identifies 74 loci associated with educational attainment
Okbay, Aysu
Beauchamp, Jonathan P.
Fontana, Mark Alan
Lee, James J.
Pers, Tune H.
Rietveld, Cornelius A.
Turley, Patrick
Chen, Guo-Bo
Emilsson, Valur
Meddens, S. Fleur W.
Oskarsson, Sven
Pickrell, Joseph K.
Thom, Kevin
Timshel, Pascal
de Vlaming, Ronald
Abdellaoui, Abdel
Ahluwalia, Tarunveer S.
Bacelis, Jonas
Baumbach, Clemens
Bjornsdottir, Gyda
Brandsma, Johannes H.
Concas, Maria Pina
Derringer, Jaime
Furlotte, Nicholas A.
Galesloot, Tessel E.
Girotto, Giorgia
Gupta, Richa
Hall, Leanne M.
Harris, Sarah E.
Hofer, Edith
Horikoshi, Momoko
Huffman, Jennifer E.
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Kalafati, Ioanna P.
Karlsson, Robert
Kong, Augustine
Lahti, Jari
van der Lee, Sven J.
de Leeuw, Christiaan
Lind, Penelope A.
Lindgren, Karl-Oskar
Liu, Tian
Mangino, Massimo
Marten, Jonathan
Mihailov, Evelin
Miller, Michael B.
van der Most, Peter J.
Oldmeadow, Christopher
Payton, Antony
Pervjakova, Natalia
NATURE, 2016, 533 (7604) : 539 - +
[2] Commentary: Genome-wide association study identifies 74 loci associated with educational attainment
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