Physical activity in advanced cancer patients: A systematic review protocol

被引：15

作者：

Lowe S.S. ^{[1
]}

Tan M. ^{[2
]}

Faily J. ^{[3
]}

Watanabe S.M. ^{[4
]}

Courneya K.S. ^{[5
]}

机构：

[1] Cross Cancer Institute, Department of Symptom Control and Palliative Care, 11560 University Avenue, Edmonton, T6G 1Z2, AB

[2] Cross Cancer Institute, Knowledge Resource Service, Knowledge Management Department, Research Innovation and Analytics, Abdul Khaliq Library, 11560 University Avenue, Edmonton, T6G 1Z2, AB

[3] Edmonton Zone Palliative Care Program-Palliative Community Consult Team (EZPCP-PCCT), 335, 1090 Youville Drive West, Edmonton, T6L 0A3, AB

[4] Cross Cancer Institute, Division of Palliative Care Medicine, Department of Oncology, University of Alberta, 11560 University Avenue, Edmonton, T6G 1Z2, AB

[5] University of Alberta, Faculty of Physical Education and Recreation, 1-113 University Hall, Edmonton, T6G 2H9, AB

来源：

Systematic Reviews | / 5卷 / 1期

关键词：

Cancer; End of life; Exercise; Neoplasms; Oncology; Palliative care; Physical activity; Quality of life; Systematic review; Terminal illness;

D O I：

10.1186/s13643-016-0220-x

中图分类号：

学科分类号：

摘要：

Background: Progressive, incurable cancer is associated with increased fatigue, increased muscle weakness, and reduced physical functioning, all of which negatively impact quality of life. Physical activity has demonstrated benefits on cancer-related fatigue and physical functioning in early-stage cancer patients; however, its impact on these outcomes in end-stage cancer has not been established. The aim of this systematic review is to determine the potential benefits, harms, and effects of physical activity interventions on quality of life outcomes in advanced cancer patients. Methods/design: A systematic review of peer-reviewed literature on physical activity in advanced cancer patients will be undertaken. Empirical quantitative studies will be considered for inclusion if they present interventional or observational data on physical activity in advanced cancer patients. Searches will be conducted in the following electronic databases: CINAHL; CIRRIE Database of International Rehabilitation Research; Cochrane Database of Systematic Reviews (CDSR); Database of Abstracts of Reviews of Effects (DARE); Cochrane Central Register of Controlled Trials (CENTRAL); EMBASE; MEDLINE; PEDro: the Physiotherapy Evidence Database; PQDT; PsycInfo; PubMed; REHABDATA; Scopus; SPORTDiscus; and Web of Science, to identify relevant studies of interest. Additional strategies to identify relevant studies will include citation searches and evaluation of reference lists of included articles. Titles, abstracts, and keywords of identified studies from the search strategies will be screened for inclusion criteria. Two independent reviewers will conduct quality appraisal using the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies (EPHPP) and the Cochrane risk of bias tool. A descriptive summary of included studies will describe the study designs, participant and activity characteristics, and objective and patient-reported outcomes. Discussion: This systematic review will summarize the current evidence base on physical activity interventions in advanced cancer patients. The findings from this systematic review will identify gaps to be explored by future research studies and inform future practice guideline development of physical activity interventions in advanced cancer patients. Systematic review registration: PROSPERO CRD42015026281 © 2016 Lowe et al.

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