Modulation of the nuclear factor-kappa B (NF-κB) signalling pathway by glutamine in peritoneal macrophages of a murine model of protein malnutrition

被引:0
作者
Fabiana da Silva Lima
Marcelo Macedo Rogero
Mayara Caldas Ramos
Primavera Borelli
Ricardo Ambrósio Fock
机构
[1] University of Sao Paulo,Experimental Hematology Laboratory, Department of Clinical and Toxicological Analyses, Faculty of Pharmaceutical Sciences
[2] University of Sao Paulo,Department of Nutrition, School of Public Health
来源
European Journal of Nutrition | 2013年 / 52卷
关键词
Protein malnutrition; Macrophages; Glutamine; NF-κB; TNF-α; IL-1α;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1343 / 1351
页数:8
相关论文
共 86 条
[1]  
Akner G(2001)Treatment of protein-energy malnutrition in chronic nonmalignant disorders Am J Clin Nutr 74 6-24
[2]  
Cederholm T(2004)Innate immunity: an overview Mol Immunol 40 845-859
[3]  
Beutler B(2000)Nutrition and infection: malnutrition and mortality in public health Nutr Rev 58 S1-S4
[4]  
Brundtland GH(2001)Malnutrition and caquexia in ovarian cancer patients: pathophysiology and management Anticancer Res 21 2941-2947
[5]  
Gadducci A(2007)Protein-energy malnutrition decreases the expression of TLR-4/MD-2 and CD14 receptors in peritoneal macrophages and reduces the synthesis of TNF-α in response to lipopolysaccharide (LPS) in mice Cytokine 40 105-114
[6]  
Cosio S(2003)History of nutrition: malnutrition, infection and immunity J Nutr 133 S336-S340
[7]  
Fanucchi A(1999)Glutamine metabolism by lymphocytes, macrophages, and neutrophils: its importance in healthy and disease Nutr Biochem 10 316-324
[8]  
Fock RA(1999)Macrophage-mediated lysis of a β-cell line, TNF-α release from BCG-actived murine macrophages and IL-8 release from human monocytes are dependent on extracellular glutamine concentration and glutamine metabolism Clin Sci 96 89-97
[9]  
Vinolo MA(2001)Why is J Nutr 131 S2515-S2522
[10]  
de Moura Sá Rocha V(1987)-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection? Biochem J 15 631-636