Talin depletion reveals independence of initial cell spreading from integrin activation and traction

被引：0
作者：
Xian Zhang
Guoying Jiang
Yunfei Cai
Susan J. Monkley
David R. Critchley
Michael P. Sheetz
机构：
[1] Columbia University,Department of Biological Sciences
[2] University of Leicester,Department of Biochemistry
来源：
Nature Cell Biology | 2008年 / 10卷
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摘要：
Talins link integrins to the actin cytoskeleton and are important for cell spreading. Sheetz and colleagues show that talin is dispensable for initial cell spreading but it is required for sustained cell spreading and adhesion.
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页码：1062 / 1068
页数：6
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