Prevention or acceleration of type 1 diabetes by viruses

被引：0
作者：
Liana Ghazarian
Julien Diana
Yannick Simoni
Lucie Beaudoin
Agnès Lehuen
机构：
[1] Hôpital Saint Vincent de Paul/Cochin,
来源：
Cellular and Molecular Life Sciences | 2013年 / 70卷
关键词：
Diabetes; Environment; Virus; Coxsackievirus;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Type 1 diabetes is an autoimmune disease characterized by the destruction of insulin-producing pancreatic β-cells. Even though extensive scientific research has yielded important insights into the immune mechanisms involved in pancreatic β-cell destruction, little is known about the events that trigger the autoimmune process. Recent epidemiological and experimental data suggest that environmental factors are involved in this process. In this review, we discuss the role of viruses as an environmental factor on the development of type 1 diabetes, and the immune mechanisms by which they can trigger or protect against this pathology.
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页码：239 / 255
页数：16
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