Water extract of the fruits of Alpinia oxyphylla inhibits osteoclast differentiation and bone loss

[1] Negishi-Koga T(2009)Ca2 + −NFATc1 signaling is an essential axis of osteoclast differentiation Immunol Rev 231 241-256

[2] Takayanagi H(2005)Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system Immunol Rev 208 30-49

[3] Tanaka S(1999)OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis Nature 397 315-323

[4] Nakamura K(1998)Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation Cell 93 165-176

[5] Takahasi N(1999)Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors J Exp Med 190 1741-1754

[6] Suda T(1993)Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors J Clin Invest 91 257-263

[7] Kong YY(2004)Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation J Clin Invest 114 475-484

[8] Yoshida H(2006)Induction of c-Fos and NFATc1 during RANKL-stimulated osteoclast differentiation is mediated by the p38 signaling pathway Biochem Biophys Res Commun 351 99-105

[9] Sarosi I(2007)NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1 J Biol Chem 282 18245-18253

[10] Tan HL(2005)RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis EMBO J 24 790-799

[1] Negishi-Koga T(2009)Ca2 + −NFATc1 signaling is an essential axis of osteoclast differentiation Immunol Rev 231 241-256

[2] Takayanagi H(2005)Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system Immunol Rev 208 30-49

[3] Tanaka S(1999)OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis Nature 397 315-323

[4] Nakamura K(1998)Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation Cell 93 165-176

[5] Takahasi N(1999)Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors J Exp Med 190 1741-1754

[6] Suda T(1993)Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors J Clin Invest 91 257-263

[7] Kong YY(2004)Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation J Clin Invest 114 475-484

[8] Yoshida H(2006)Induction of c-Fos and NFATc1 during RANKL-stimulated osteoclast differentiation is mediated by the p38 signaling pathway Biochem Biophys Res Commun 351 99-105

[9] Sarosi I(2007)NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1 J Biol Chem 282 18245-18253

[10] Tan HL(2005)RANK-mediated amplification of TRAF6 signaling leads to NFATc1 induction during osteoclastogenesis EMBO J 24 790-799