Inhibition of IGF1-R overcomes IGFBP7-induced chemotherapy resistance in T-ALL

[1] Gökbuget N(2009)Treatment of adult acute lymphoblastic leukemia Semin Hematol 46 64-75

[2] Hoelzer D(2004)Better outcome of adult acute lymphoblastic leukemia after early genoidentical allogeneic bone marrow transplantation (BMT) than after late high-dose therapy and autologous BMT: a GOELAMS trial Blood 104 3028-3037

[3] Hunault M(2011)The IGF system Acta Diabetol 48 1-9

[4] Harousseau J-L(1999)The insulin-like growth factor-binding protein (IGFBP) superfamily Endocr Rev 20 761-787

[5] Delain M(2000)Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities Am J Physiol - Endocrinol Metab 278 E967-E976

[6] Truchan-Graczyk M(2010)Identification of a Novel Cell Death Receptor Mediating IGFBP-3-induced Antitumor Effects in Breast and Prostate Cancer J Biol Chem 285 30233-30246

[7] Cahn J-Y(2000)Nuclear import of insulin-like growth factor-binding protein-3 and −5 is mediated by the importin beta subunit J Biol Chem 275 23462-23470

[8] Witz F(2014)IGFBP-2 nuclear translocation is mediated by a functional NLS sequence and is essential for its pro-tumorigenic actions in cancer cells Oncogene 33 578-588

[9] Annunziata M(2001)Downregulation of the potential suppressor gene IGFBP-rP1 in human breast cancer is associated with inactivation of the retinoblastoma protein, cyclin E overexpression and increased proliferation in estrogen receptor negative tumors Oncogene 20 3497-3505

[10] Granata R(2007)IGFBP7 Plays a Potential Tumor Suppressor Role in Colorectal Carciogenesis Cancer Biol Ther 6 354-359

[1] Gökbuget N(2009)Treatment of adult acute lymphoblastic leukemia Semin Hematol 46 64-75

[2] Hoelzer D(2004)Better outcome of adult acute lymphoblastic leukemia after early genoidentical allogeneic bone marrow transplantation (BMT) than after late high-dose therapy and autologous BMT: a GOELAMS trial Blood 104 3028-3037

[3] Hunault M(2011)The IGF system Acta Diabetol 48 1-9

[4] Harousseau J-L(1999)The insulin-like growth factor-binding protein (IGFBP) superfamily Endocr Rev 20 761-787

[5] Delain M(2000)Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities Am J Physiol - Endocrinol Metab 278 E967-E976

[6] Truchan-Graczyk M(2010)Identification of a Novel Cell Death Receptor Mediating IGFBP-3-induced Antitumor Effects in Breast and Prostate Cancer J Biol Chem 285 30233-30246

[7] Cahn J-Y(2000)Nuclear import of insulin-like growth factor-binding protein-3 and −5 is mediated by the importin beta subunit J Biol Chem 275 23462-23470

[8] Witz F(2014)IGFBP-2 nuclear translocation is mediated by a functional NLS sequence and is essential for its pro-tumorigenic actions in cancer cells Oncogene 33 578-588

[9] Annunziata M(2001)Downregulation of the potential suppressor gene IGFBP-rP1 in human breast cancer is associated with inactivation of the retinoblastoma protein, cyclin E overexpression and increased proliferation in estrogen receptor negative tumors Oncogene 20 3497-3505

[10] Granata R(2007)IGFBP7 Plays a Potential Tumor Suppressor Role in Colorectal Carciogenesis Cancer Biol Ther 6 354-359