Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination

被引：0

作者：

Sha Mi

Xinhua Lee

Yinghui Hu

Benxiu Ji

Zhaohui Shao

Weixing Yang

Guanrong Huang

Lee Walus

Kenneth Rhodes

Bang Jian Gong

Robert H Miller

R Blake Pepinsky

机构：

[1] Biogen Idec,Department of Neurosciences

[2] Center for Translational Neuroscience,undefined

[3] Case Western Reserve University School of Medicine,undefined

来源：

Nature Medicine | 2011年 / 17卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The multiple sclerosis brain shows massive demyelination. Now, Sha Mi and colleagues show that upregulation of DR6 in multiple sclerosis brain is responsible for inhibiting remyelination and brain repair by oligodendrocytes.

引用

页码：816 / 821

页数：5

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