Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice

被引:0
作者
Yongkang Fang
Yeye Tian
Qibao Huang
Yue Wan
Li Xu
Wei Wang
Dengji Pan
Suiqiang Zhu
Minjie Xie
机构
[1] Huazhong University of Science and Technology,Department of Neurology, Tongji Hospital, Tongji Medical College
[2] Wuhan University of Science and Technology,College of medicine
[3] The Third People’s Hospital of Hubei Province,Department of Neurology
来源
Journal of Neuroinflammation | / 16卷
关键词
TREK-1; Intracerebral hemorrhage; Secondary injury; Inflammation; Blood-brain barrier;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 291 条
[1]  
Hanggi D(2008)Spontaneous intracerebral haemorrhage in adults: a literature overview Acta Neurochirurgica 150 371-379
[2]  
Steiger HJ(2016)Intracerebral hemorrhage: perihemorrhagic edema and secondary hematoma expansion: from bench work to ongoing controversies Front Neurol 7 210-77
[3]  
Mittal MK(2014)Vascular disruption and blood-brain barrier dysfunction in intracerebral hemorrhage Fluids Barriers CNS 11 18-122
[4]  
LacKamp A(2008)Blood-brain barrier function in intracerebral hemorrhage Cerebral Hemorrhage 105 73-114
[5]  
Keep RF(2015)Targeting secondary injury in intracerebral haemorrhage[mdash]perihaematomal oedema Nat Rev Neurol 11 111-5157
[6]  
Zhou N(2001)Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery Brain Res Mol Brain Res 86 101-122
[7]  
Xiang J(2015)Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K+ Channel 1). A Novel Therapeutic Target? Journal of Medicinal Chemistry 59 5149-251
[8]  
Andjelkovic AV(2014)The thermosensitive potassium channel TREK-1 contributes to coolness-evoked responses of Grueneberg ganglion neurons Cell Mol Neurobiol 34 113-1141
[9]  
Hua Y(2006)Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia Neuroscience 137 241-2695
[10]  
Xi G(2006)Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype Nat Neurosci 9 1134-2376