Development of Hippocampus-Associated Cognitive Dysfunction in Huntington’s Disease Mouse Model

被引:0
作者
N. A. Kraskovskaya
A. I. Erofeev
E. D. Grishina
S. A. Pushkareva
E. I. Gerasimov
O. L. Vlasova
I. B. Bezprozvanny
机构
[1] Peter the Great St. Petersburg Polytechnic University,
[2] Department of Physiology,undefined
[3] UT Southwestern Medical Center at Dallas,undefined
来源
Journal of Evolutionary Biochemistry and Physiology | 2021年 / 57卷
关键词
Huntington’s disease; hippocampus; long-term potentiation; dendritic spines; Morris water maze; cognitive impairment; behavioral tests;
D O I
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中图分类号
学科分类号
摘要
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页码:1449 / 1460
页数:11
相关论文
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[1]  
The Huntington’s Disease Collaborative Research Group(1993)A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes Cell 72 971-983
[2]  
Van Raamsdonk JM(2007)Selective degeneration in YAC mouse models of Huntington disease Brain Res Bull 72 124-131
[3]  
Warby SC(2005)Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington’s disease J Neurosci 25 4169-4180
[4]  
Hayden MR(2010)Before chorea: pre-Huntington mild cognitive impairment Neurology 75 490-491
[5]  
Van Raamsdonk JM(1998)Evidence for specific cognitive deficits in preclinical Huntington’s disease Brain 121 1329-1341
[6]  
Pearson J(2013)Dysregulation of synaptic proteins, dendritic spine abnormalities and pathological plasticity of synapses as experience-dependent mediators of cognitive and psychiatric symptoms in Huntington’s disease Neuroscience 251 66-74
[7]  
Slow EJ(2016)Dendritic Spines as Tunable Regulators of Synaptic Signals Front Psychiatry 7 101-141
[8]  
Hossain SM(2016)Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington’s Disease Mouse Model J Neurosci 36 125-969
[9]  
Leavitt BR(2003)Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington’s disease J Neurosci 23 961-2966
[10]  
Hayden MR(2015)Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington’s disease J Neurophysiol 113 2953-13009