Base-oxidant promoted metal-free N-demethylation of arylamines

被引：0
|
作者：
VINAYAK BOTLA
CHIRANJEEVI BARREDDI
RAMANA V DAGGUPATI
CHANDRASEKHARAM MALAPAKA
机构：
[1] I&PC Division,
[2] CSIR-Indian Institute of Chemical Technology,undefined
来源：
Journal of Chemical Sciences | 2016年 / 128卷
关键词：
, ; -dialkylaniline; -dealkylation; Triethylamine; -butyl hydroperoxide; metal-free.;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A metal-free oxidative N-demethylation of arylamines with triethylamine as a base and tert-butyl hydroperoxide (TBHP) as oxidant is reported in this paper. The reaction is general, practical, inexpensive, non-toxic, and the method followed is environmentally benign, with moderate to good yields.
引用
收藏
页码：1469 / 1473
页数：4
相关论文
共 50 条
  • [1] Base-oxidant promoted metal-free N-demethylation of arylamines
    Botla, Vinayak
    Barreddi, Chiranjeevi
    Daggupati, Ramana V.
    Malapaka, Chandrasekharam
    JOURNAL OF CHEMICAL SCIENCES, 2016, 128 (09) : 1469 - 1473
  • [2] CuCl-catalyzed Oxidative N-Demethylation of Arylamines with tButyl Hydroperoxide
    LIAO Qian and XI Chan-juan Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology
    ChemicalResearchinChineseUniversities, 2009, 25 (06) : 861 - 865
  • [3] CuCl-catalyzed Oxidative N-Demethylation of Arylamines with tButyl Hydroperoxide
    Liao Qian
    Xi Chan-juan
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2009, 25 (06) : 861 - 865
  • [4] Studies towards DIAD promoted N-demethylation of N,N-dimethylanilines
    Ren, Jiangmeng
    Cao, Fu-Rong
    Sun, Xue-Qin
    Xu, Xuan
    Liu, Gui-Xia
    Zeng, Bu-Bing
    TETRAHEDRON LETTERS, 2022, 103
  • [5] Base-Promoted Metal-Free Arylation of Benzoxazoles with Phenylglyoxylic Acids
    Yang, Zhiyong
    Zhou, Liang
    Liu, Ying
    Lu, Hongwen
    Wu, Fengxuan
    Xie, Yuxin
    Liu, Jianle
    CHEMISTRYSELECT, 2019, 4 (47): : 13788 - 13791
  • [6] Metal-Free Insertion of Sulfoxonium Ylides into Arylamines in Water
    He, Hua
    Yan, Kaichuan
    Li, Jianglian
    Lai, Ruizhi
    Luo, Yi
    Guan, Mei
    Wu, Yong
    SYNTHESIS-STUTTGART, 2020, 52 (20): : 3065 - 3070
  • [7] Copper-Catalyzed Radical N-Demethylation of Amides Using N-Fluorobenzenesulfonimide as an Oxidant
    Yi, Xuewen
    Lei, Siyu
    Liu, Wangsheng
    Che, Fengrui
    Yu, Chunzheng
    Liu, Xuesong
    Wang, Zonghua
    Zhou, Xin
    Zhang, Yuexia
    ORGANIC LETTERS, 2020, 22 (12) : 4583 - 4587
  • [8] Metal-Free Oxidative C-C Coupling of Arylamines Using a Quinone-Based Organic Oxidant
    Maddala, Sudhakar
    Mallick, Sudesh
    Venkatakrishnan, Parthasarathy
    JOURNAL OF ORGANIC CHEMISTRY, 2017, 82 (17): : 8958 - 8972
  • [9] Base-promoted synthesis of dibenzoxazepinamines and quinazolinimines under metal-free conditions
    Feng, Jian-Bo
    Wu, Xiao-Feng
    GREEN CHEMISTRY, 2015, 17 (09) : 4522 - 4526
  • [10] Metal-free base-promoted sulfenylation for the synthesis of α-arylthio-α,β-unsaturated ketones
    Zhu, Xiao-Tong
    Zhao, Qi
    Wang, Shi-Da
    Zhang, Tian-Shu
    Cai, Pei-Jun
    Hao, Wen-Juan
    Tu, Shu-Jiang
    Jiang, Bo
    TETRAHEDRON, 2018, 74 (05) : 585 - 593
12345