Synthesis of 5-(4-aminophenyl)-2-(arylamino)-1,3,4-thiadiazoles and their schiff base derivatives as antimycobacterial agents

被引：0
|
作者：
K. A. Dilmaghani
N. H. Jazani
F. Nasuhi Pur
N. Shokoufeh
F. Ghadiri
F. M. Fakhraee
机构：
[1] Urmia University,
[2] Urmia Medical Science University,undefined
[3] Institute of Standard and Industrial Research of Iran,undefined
来源：
Chemistry of Heterocyclic Compounds | 2012年 / 48卷
关键词：
salicylaldehyde; 1,3,4-thiadiazole; Schiff base;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The condensation reaction of 5-(4-aminophenyl)-N-aryl-1,3,4-thiadiazol-2-ylamines with salicyl-aldehyde, 3-hydroxybenzaldehyde, 4-hydroxybenzaldehyde, 5-bromosalicylaldehyde, 5-chlorosalicyl-aldehyde, 4-methoxybenzaldehyde, 3-nitrobenzaldehyde, and 4-nitrobenzaldehyde results in series of new Schiff bases. The synthesized compounds were tested for their antimicrobial efficiency against Mycobacterium smegmatis PTCC 1307 in vitro. All compounds showed significant antiproliferative activity against M. smegmatis.
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页码：362 / 367
页数：5
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