B-Type Natriuretic Peptide as Biomarker of Fetal Cardiovascular Distress

被引：0

作者：

D C Vijlbrief

M J N L Benders

H Kemperman

F Van Bel

W B De Vries

机构：

[1] Neonatology,

[2] University Medical Center Utrecht,undefined

[3] Clinical Chemistry and Hematology,undefined

[4] University Medical Center Utrecht,undefined

来源：

Pediatric Research | 2011年 / 70卷

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摘要：

Background: Early life exposure to a (chronic) hypoxic incident may predispose to adult cardiovascular risk. Identifying those at risk is difficult. Impairment of gas exchange and blood flow through the placenta leads to hypoxia and hypercapnia. If hypoxia persists, depletion of energy reserves and anaerobic metabolism with lactate acidosis directly affects myocardial contractility. B-type natriuretic peptide (BNP), a biomarker of ventricular strain, is used to recognise cardiocirculatory failure.

引用

页码：236 / 236