One-Pot Synthesis of Glycyrrhetinic Acid from Licorice Root in Subcritical Water

被引：0

作者：

A. V. Lekar

E. V. Maksimenko

S. N. Borisenko

S. S. Khizrieva

E. V. Vetrova

N. I. Borisenko

V. I. Minkin

机构：

[1] Institute of Physical and Organic Chemistry,

[2] Southern Federal University,undefined

来源：

Russian Journal of Physical Chemistry B | 2019年 / 13卷

关键词：

one-pot; glycyrrhetinic acid; glycyrrhizinic acid; subcritical water; roots of licorice ; L.;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Abstract—Glycyrrhetinic acid (GLA) was synthesized in a good yield from the roots of licorice Glycyrrhiza glabra L. by the one-pot method in subcritical water (SCW), which served as a reagent and solvent. This method for the synthesis of GLA makes it possible to avoid the use of expensive and toxic organic solvents and does not require separate extraction and hydrolysis stages. GLA is obtained in good yields within periods of time ten times shorter than needed when using conventional procedures. The method is promising for future development of inexpensive and environmentally friendly technologies for the synthesis of GLA and its derivatives in pharmaceutical, food, and cosmetic industries.

引用

收藏

页码：1150 / 1154

页数：4

相关论文

共 50 条

[21] One-pot synthesis of sulfonylhydrazones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water [J].

Mengqiang Luo ;

Hai Wang ;

Xiaorong Ren ;

Ruijuan Lu ;

Chenze Qi ;

Yaohong Zhang ;

Runpu Shen .

Journal of the Iranian Chemical Society, 2021, 18 :2713-2722

[22] One-pot synthesis of sulfonylhydrazones from sulfonyl chloride, hydrazine hydrate and vinyl azide in water [J].

Luo, Mengqiang ;

Wang, Hai ;

Ren, Xiaorong ;

Lu, Ruijuan ;

Qi, Chenze ;

Zhang, Yaohong ;

Shen, Runpu .

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2021, 18 (10) :2713-2722

[23] One-pot synthesis of epoxides from benzyl alcohols and aldehydes [J].

Alfonzo, Edwin ;

Mendoza, Jesse W. L. ;

Beeler, Aaron B. .

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2018, 14 :2308-2312

[24] One-pot synthesis of vicinal aminoalkanols from sugar aldehydes [J].

Soengas, Raquel G. ;

Silva, Artur M. S. .

TETRAHEDRON, 2013, 69 (16) :3425-3431

[25] Facile one-pot synthesis of aryl azides from nitrobenzenes [J].

Zhao, Fen ;

Chen, Zhen ;

Lei, Pengfei ;

Kong, Linglei ;

Jiang, Yubo .

TETRAHEDRON LETTERS, 2015, 56 (17) :2197-2199

[26] Optimized ultrasound-assisted extraction of glycyrrhizic acid from Glycyrrhiza glabra followed by one-pot hydrolysis to and nanoemulsified separation of glycyrrhetinic acid for food applications [J].

Habibi, Maysam ;

Dehghan, Hossein ;

Rahimi, Masoud ;

Rafati, Hasan .

JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2024,

[27] HIGHLY EFFICIENT ONE-POT SYNTHESIS OF α-AMINOPHOSPHONATES CATALYZED BY YTTERBIUM TRIFLATE IN WATER [J].

Shen, MingGui ;

Shang, ShiBin ;

Song, ZhanQian ;

Wang, Dan ;

Rao, XiaoPing ;

Gao, Hong ;

Wang, Juan .

SYNTHETIC COMMUNICATIONS, 2014, 44 (03) :361-367

[28] One-Pot Synthesis of α-Ylidene δ-Lactones from Functionalized Allylic Bromides in a Water-Isopropanol Medium [J].

Ferreira M. ;

Bisol T.B. ;

Da Conceição H.P. ;

Russo T.V.C. ;

Bortoluzzi A.J. ;

Sá M.M. .

Synthesis (Germany), 2017, 49 (03) :667-676

[29] A convenient one-pot synthesis of ethylene blue [J].

Cody, Jeremy A. ;

Larrabee, Christian S. ;

Clark, Michael D. ;

Hlynchuk, Sofiya ;

Tatum, Jacob A. .

TETRAHEDRON LETTERS, 2012, 53 (36) :4896-4899

[30] One-Pot Synthesis of β-Alanine from Maleic Acid via Three-Enzyme Cascade Biotransformation [J].

Wu, Jia ;

Ma, Bao-Di ;

Xu, Yi .

CATALYSTS, 2023, 13 (02)

← 1 2 3 4 5 →