Identification of potential resistance mechanisms and therapeutic targets for the relapse of BCMA CAR-T therapy in relapsed/refractory multiple myeloma through single-cell sequencing

被引:0
作者
Wei Li
Binglei Zhang
Weijie Cao
Wenli Zhang
Tiandong Li
Lina Liu
LinPing Xu
Fengcai Gao
Yanmei Wang
Fang Wang
Haizhou Xing
Zhongxing Jiang
Jianxiang Shi
Zhilei Bian
Yongping Song
机构
[1] The First Affiliated Hospital of Zhengzhou University,Department of Hematology
[2] Henan Provincial Hematology Hospital,Department of Hematology
[3] Zhengzhou University,BGI College & Henan Institute of Medical and Pharmaceutical Sciences in Academy of Medical Science
[4] The Affiliated Cancer Hospital of Zhengzhou University,Department of Hematology
[5] Zhengzhou University,College of Public Health
[6] The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital,Department of Research and Foreign Affairs
[7] Zhengzhou People’s Hospital,Department of Hematology
来源
Experimental Hematology & Oncology | / 12卷
关键词
BCMA CAR-T; Multiple myeloma; Resistant mechanisms; ScRNA-seq; T cell exhaustion; Monocyte/macrophages;
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