Validation of Plasmodium falciparum dUTPase as the target of 5′-tritylated deoxyuridine analogues with anti-malarial activity

被引:0
作者
Guiomar Pérez-Moreno
Paula Sánchez-Carrasco
Luis Miguel Ruiz-Pérez
Nils Gunnar Johansson
Sylke Müller
Beatriz Baragaña
Shahienaz Emma Hampton
Ian Hugh Gilbert
Marcel Kaiser
Sandipan Sarkar
Thiyagamurthy Pandurangan
Vijeesh Kumar
Dolores González-Pacanowska
机构
[1] Instituto de Parasitología y Biomedicina López-Neyra. Consejo Superior de Investigaciones Científicas. Parque Tecnológico de Ciencias de la Salud,Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences
[2] Medivir AB,Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences
[3] University of Glasgow,undefined
[4] University of Dundee,undefined
[5] Swiss Tropical and Public Health Institute (Swiss TPH),undefined
[6] University of Basel,undefined
[7] Syngene International Ltd,undefined
来源
Malaria Journal | / 18卷
关键词
Deoxyuridine 5′-triphosphate nucleotido-hydrolase; 5′-tritylated deoxyuridine analogues; Mode of action;
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