High Prevalence of GB Virus C/Hepatitis G Virus RNA and Antibodies in Patients Infected with Human Immunodeficiency Virus Type 1

被引:0
作者
D. Rey
J. Vidinic-Moularde
P. Meyer
C. Schmitt
S. Fritsch
J. M. Lang
F. Stoll-Keller
机构
[1] CISIH,
[2] Clinique Médicale A,undefined
[3] Hôpitaux Universitaires,undefined
[4] 1 place de l'Hôpital,undefined
[5] 67091 Strasbourg Cedex,undefined
[6] France e-mail: david.rey@chru-strasbourg.fr,undefined
[7] Institut de Virologie,undefined
[8] Faculté de Médecine,undefined
[9] 3 rue Koeberlé,undefined
[10] 67000 Strasbourg,undefined
[11] France,undefined
[12] Département d'Information Médicale,undefined
[13] Hôpitaux Universitaires,undefined
[14] 1 place de l'Hôpital,undefined
[15] 67091 Strasbourg Cedex,undefined
[16] France,undefined
来源
European Journal of Clinical Microbiology and Infectious Diseases | 2000年 / 19卷
关键词
Hepatitis; Human Immunodeficiency Virus; Cell Count; Human Immunodeficiency Virus Type; Virus Type;
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摘要
 The prevalence of GB virus C (GBV-C)/ hepatitis G virus (HGV) RNA and antibodies to the structural E2 protein was investigated in a cohort of HIV-1 infected patients. Of 346 individuals, RNA was detected in 143 and E2 antibodies were detected in 73, for an overall prevalence of 62.4%. Intravenous drug use and homosexuality were identified as major transmission risk factors. GBV-C/HGV RNA prevalence was associated with hepatitis B coinfection, whereas antibodies to E2 were associated with older age and lower CD4+ cell counts. GBV-C/HGV infection was frequent in this group of HIV-infected patients and was associated with older age, lower CD4+ cell counts, and the presence of hepatitis B surface antigen.
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页码:721 / 724
页数:3
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