Initial 3-Weeks’ Apixaban Versus Dual-Antiplatelet Therapy (Clopidogrel and Aspirin) Followed by Clopidogrel Alone in High-Risk Patients with Acute Non-Disabling Cerebrovascular Events (ADANCE): Study Protocol for a Randomized Controlled Trial

被引:0
作者
Fang Yang
Hui Lei
Wenrui Jiang
Wen Jiang
Junliang Han
Gang Zhao
机构
[1] Xijing Hospital,Department of Neurology
[2] Xi’an Center Hospital,Department of Neurology
[3] Tangdu Hospital,Department of Cardiology
来源
Clinical Drug Investigation | 2014年 / 34卷
关键词
Clopidogrel; Transient Ischemic Attack; Apixaban; Recurrent Stroke; DAPT;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:755 / 761
页数:6
相关论文
共 39 条
[1]  
Rothwell PM(2006)Recent advances in management of transient ischaemic attacks and minor ischaemic strokes Lancet Neurol 5 323-331
[2]  
Buchan A(2000)Short-term prognosis after emergency department diagnosis of TIA JAMA 284 2901-2906
[3]  
Johnston SC(2005)Intravenous heparin started within the first 3 hours after onset of symptoms as a treatment for acute nonlacunar hemispheric cerebral infarctions Stroke 36 2415-2420
[4]  
Johnston SC(2000)Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: a double-blind randomised study. HAEST Study Group. Heparin in acute embolic stroke trial Lancet 355 1205-1210
[5]  
Gress DR(2012)Bleeding during treatment with aspirin versus apixaban in patients with atrial fibrillation unsuitable for warfarin: the apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K antagonist treatment (AVERROES) trial Stroke 43 3291-3297
[6]  
Browner WS(2006)Improving the quality of consent to randomised controlled trials by using continuous consent and clinician training in the consent process J Med Ethics 32 439-443
[7]  
Sidney S(2007)Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack Lancet 369 283-292
[8]  
Camerlingo M(2007)Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial Lancet Neurol 6 961-969
[9]  
Salvi P(2013)Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association Stroke 44 870-947
[10]  
Belloni G(1996)A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee Lancet 348 1329-1339