The phosphatidylserine receptor: a crucial molecular switch?

被引：0
|
作者：
Peter M. Henson
Donna L. Bratton
Valerie A. Fadok
机构：
[1] Program in Cell Biology,the Department of Pediatrics
[2] National Jewish Medical and Research Center,undefined
来源：
Nature Reviews Molecular Cell Biology | 2001年 / 2卷
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摘要：
The uptake and removal of necrotic or lysed cells involves inflammation and an immune response, due in part to processes that involve members of the collectin family, surface calreticulin and CD91. Clearance of apoptotic cells, by contrast, does not induce either inflammation or immunity. Could the phosphatidylserine receptor be the molecular switch that determines what the outcome will be?
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页码：627 / 633
页数：6
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