Omega-3 fatty acids are a potential therapy for patients with sickle cell disease

[1] Kato GJ(2018)Sickle cell disease Nat. Rev. Dis. Primers 4 18010-974

[2] Tomer A(2001)Reduction of pain episodes and prothrombotic activity in sickle cell disease by dietary n-3 fatty acids Thromb. Haemost. 85 966-44

[3] Daak AA(2012)Effect of omega-3 (n-3) fatty acid supplementation in patients with sickle cell anemia: randomized, double-blind, placebo-controlled trial Am. J. Clin. Nutr. 97 37-1616

[4] Sins JWR(2017)Pharmacotherapeutical strategies in the prevention of acute, vaso-occlusive pain in sickle cell disease: a systematic review Blood Adv. 1 1598-583

[5] Ren H(2005)Blood mononuclear cells and platelets have abnormal fatty acid composition in homozygous sickle cell disease Ann. Hematol. 84 578-73

[6] Kuypers FA(2007)Membrane lipid alterations in hemoglobinopathies Hematology Am. Soc. Hematol. Educ. Program 2007 68-484

[7] Calder PC(2015)Marine omega-3 fatty acids and inflammatory processes: effects, mechanisms and clinical relevance Biochim. Biophys. Acta 1851 469-327

[8] Buckley CD(2014)Proresolving lipid mediators and mechanisms in the resolution of acute inflammation Immunity 40 315-2067

[9] Gilroy DW(2011)Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events J. Am. Coll. Cardiol. 58 2047-55

[10] Serhan CN(2015)Omega 3 (n-3) fatty acids down-regulate nuclear factor-kappa B (NF-kappaB) gene and blood cell adhesion molecule expression in patients with homozygous sickle cell disease Blood Cells Mol. Dis. 55 48-311

[1] Kato GJ(2018)Sickle cell disease Nat. Rev. Dis. Primers 4 18010-974

[2] Tomer A(2001)Reduction of pain episodes and prothrombotic activity in sickle cell disease by dietary n-3 fatty acids Thromb. Haemost. 85 966-44

[3] Daak AA(2012)Effect of omega-3 (n-3) fatty acid supplementation in patients with sickle cell anemia: randomized, double-blind, placebo-controlled trial Am. J. Clin. Nutr. 97 37-1616

[4] Sins JWR(2017)Pharmacotherapeutical strategies in the prevention of acute, vaso-occlusive pain in sickle cell disease: a systematic review Blood Adv. 1 1598-583

[5] Ren H(2005)Blood mononuclear cells and platelets have abnormal fatty acid composition in homozygous sickle cell disease Ann. Hematol. 84 578-73

[6] Kuypers FA(2007)Membrane lipid alterations in hemoglobinopathies Hematology Am. Soc. Hematol. Educ. Program 2007 68-484

[7] Calder PC(2015)Marine omega-3 fatty acids and inflammatory processes: effects, mechanisms and clinical relevance Biochim. Biophys. Acta 1851 469-327

[8] Buckley CD(2014)Proresolving lipid mediators and mechanisms in the resolution of acute inflammation Immunity 40 315-2067

[9] Gilroy DW(2011)Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events J. Am. Coll. Cardiol. 58 2047-55

[10] Serhan CN(2015)Omega 3 (n-3) fatty acids down-regulate nuclear factor-kappa B (NF-kappaB) gene and blood cell adhesion molecule expression in patients with homozygous sickle cell disease Blood Cells Mol. Dis. 55 48-311