Hypokalemic alkalosis with hypocalciuria and normomagnesemia: A subgroup of Gitelman's syndrome?

被引：0

作者：

Maki K. ^{[1
]}

Ukimura N. ^{[1
]}

Katori Y. ^{[1
]}

Akiyama M. ^{[1
]}

Shiraishi J. ^{[1
]}

Sudo Y. ^{[1
]}

Sato T. ^{[1
]}

Nakagawa C. ^{[1
]}

Akamatsu N. ^{[1
]}

Yoneda Y. ^{[1
]}

Takada O. ^{[1
]}

Hiramori N. ^{[1
]}

Sawada K. ^{[1
]}

机构：

[1] Department of Internal Medicine, Ohmi-Hachiman City Hospital, Ohmi-Hachiman, Shiga 523-0892

来源：

Clinical and Experimental Nephrology | 1999年 / 3卷 / 1期

关键词：

Distal convoluted tubule; Gitelman's syndrome; Hypocalciuria; Hypokalemia; Normomagnesemia;

D O I：

10.1007/s101570050008

中图分类号：

学科分类号：

摘要：

We report a normomagnesemic patient with low normal blood pressure, hypokalemic alkalosis, hyperreninemia, hyperaldosteronism, and hypocalciuria. In renal clearance studies, distal delivery increased well and fractional distal solute reabsorption was dramatically diminished after the administration of furosemide, whereas thiazide produced no change in distal delivery and a moderate decrease in fractional distal solute reabsorption. These findings suggested that there may have been a defective locus in some part of the thiazide-sensitive segment of the distal convoluted tubule. As the features in this patient appear to be similar to those in Gitelman's syndrome, it is appropriate to designate this case, characterized by lack of hypomagnesemia, as a subgroup of Gitelman's syndrome.

引用

页码：46 / 50

页数：4