Study of a recombinant CHO cell line producing a monoclonal antibody by ATF or TFF external filter perfusion in a WAVE Bioreactor™

被引:12
|
作者
Marie-Françoise Clincke
Carin Mölleryd
Ye Zhang
Eva Lindskog
Kieron Walsh
Véronique Chotteau
机构
[1] Royal Institute of Technology (KTH),School of Biotechnology, Animal Cell Technology Group
[2] GE Healthcare Bio-Sciences AB,undefined
[3] GE Healthcare Bio-Sciences Corp,undefined
关键词
Cell Density; High Cell Density; Maximal Cell Density; Irvine Scientific; Tangential Flow Filtration;
D O I
10.1186/1753-6561-5-S8-P105
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  • [1] Very high density of CHO cells in perfusion by ATF or TFF in WAVE bioreactor. Part I. Effect of the cell density on the process
    Clincke, Marie-Francoise
    Molleryd, Carin
    Zhang, Ye
    Lindskog, Eva
    Walsh, Kieron
    Chotteau, Veronique
    BIOTECHNOLOGY PROGRESS, 2013, 29 (03) : 754 - 767