Experimental Evaluation of Rat Cord Blood as a Source of Stem Cells Stimulating Regeneration of the Bone Tissue

被引：0
|
作者：
A. V. Melnikova
A. G. Khasanov
A. I. Sendik
S. V. Sibiryak
机构：
[1] Bashkir State Medical University,
[2] Institute of Biochemistry and Genetics,undefined
[3] Ufa Research Center of the Russian Academy of Sciences,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2010年 / 149卷
关键词：
stem cells of the blood; bone regeneration;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We studied subpopulation structure of rat cord blood and its effects on regeneration of the bone tissue. In cord blood leukocytes, cell fractions with phenotypes CD45+/CD90−, CD45−/CD90+, CD34+/CD45+ were determined. The cells adhered to plastic during culturing and had a fibroblast-like morphology. Transplantation of rat cord blood cells into modeled femoral bone defects stimulated regeneration of the bone tissue and led to recovery of its anatomical integrity, which was confirmed by X-ray examination and histological analysis. No complete recovery of the bone structure was observed in controls (without cell implantation).
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页码：502 / 504
页数：2
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