Unique functions of CHK1 and WEE1 underlie synergistic anti-tumor activity upon pharmacologic inhibition

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作者
Amy D Guertin
Melissa M Martin
Brian Roberts
Melissa Hurd
Xianlu Qu
Nathan R Miselis
Yaping Liu
Jing Li
Igor Feldman
Yair Benita
Andrew Bloecher
Carlo Toniatti
Stuart D Shumway
机构
[1] Merck Research Laboratories,Department of Oncology
[2] Amgen,Department of In Vivo Pharmacology
[3] Hudson Alpha Institute,Molecular Biomarkers
[4] Merck Research Laboratories,Screening and Protein Sciences
[5] Merck Research Laboratories,Informatics and Analysis
[6] Merck Research Laboratories,undefined
[7] Merck Research Laboratories,undefined
[8] Institute for Applied Cancer Science,undefined
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LoVo Cell; Sensitive Cell Line; Checkpoint Kinase; CHK1 Inhibitor; CHK1 Kinase;
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