Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax

被引:0
|
作者
Vered Domankevich
Yarden Opatowsky
Assaf Malik
Abraham B. Korol
Zeev Frenkel
Irena Manov
Aaron Avivi
Imad Shams
机构
[1] University of Haifa,Institute of Evolution & Department of Evolutionary and Environmental Biology
[2] Bar-Ilan University,Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute
来源
关键词
P53; Hypoxia; Oxidative stress; RPA70; TAD2; Convergent evolution; Cancer resistance; Longevity;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 29 条
  • [1] Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax
    Domankevich, Vered
    Opatowsky, Yarden
    Malik, Assaf
    Korol, Abraham B.
    Frenkel, Zeev
    Manov, Irena
    Avivi, Aaron
    Shams, Imad
    BMC EVOLUTIONARY BIOLOGY, 2016, 16
  • [2] Adaptive methylation regulation of p53 pathway in sympatric speciation of blind mole rats, Spalax
    Zhao, Yang
    Tang, Jia-Wei
    Yang, Zhi
    Cao, Yi-Bin
    Ren, Ji-Long
    Ben-Abu, Yuval
    Li, Kexin
    Chen, Xue-Qun
    Du, Ji-Zeng
    Nevo, Eviatar
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (08) : 2146 - 2151
  • [3] Transcription Pattern of p53-Targeted DNA Repair Genes in the Hypoxia-Tolerant Subterranean Mole Rat Spalax
    Shams, Imad
    Malik, Assaf
    Manov, Irena
    Joel, Alma
    Band, Mark
    Avivi, Aaron
    JOURNAL OF MOLECULAR BIOLOGY, 2013, 425 (07) : 1111 - 1118
  • [4] Resistance to DNA damage and enhanced DNA repair capacity in the hypoxia-tolerant blind mole rat Spalax carmeli
    Domankevich, Vered
    Eddini, Hossam
    Odeh, Amani
    Shams, Imad
    JOURNAL OF EXPERIMENTAL BIOLOGY, 2018, 221 (08):
  • [5] The Muscle Ankyrin Repeat Proteins Are Hypoxia-Sensitive: In Vivo mRNA Expression in the Hypoxia-Tolerant Blind Subterranean Mole Rat, Spalax ehrenbergi
    Mark Band
    Alma Joel
    Aaron Avivi
    Journal of Molecular Evolution, 2010, 70 : 1 - 12
  • [6] The Muscle Ankyrin Repeat Proteins Are Hypoxia-Sensitive: In Vivo mRNA Expression in the Hypoxia-Tolerant Blind Subterranean Mole Rat, Spalax ehrenbergi
    Band, Mark
    Joel, Alma
    Avivi, Aaron
    JOURNAL OF MOLECULAR EVOLUTION, 2010, 70 (01) : 1 - 12
  • [7] Genome maintenance and bioenergetics of the long-lived hypoxia-tolerant and cancer-resistant blind mole rat, Spalax: a cross-species analysis of brain transcriptome
    Assaf Malik
    Vered Domankevich
    Han Lijuan
    Fang Xiaodong
    Abraham Korol
    Aaron Avivi
    Imad Shams
    Scientific Reports, 6
  • [8] Genome maintenance and bioenergetics of the long-lived hypoxia-tolerant and cancer-resistant blind mole rat, Spalax: a cross-species analysis of brain transcriptome
    Malik, Assaf
    Domankevich, Vered
    Han Lijuan
    Fang Xiaodong
    Korol, Abraham
    Avivi, Aaron
    Shams, Imad
    SCIENTIFIC REPORTS, 2016, 6
  • [9] Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein
    Marian M. Deuker
    Kaitlyn N. Lewis
    Maria Ingaramo
    Jacob Kimmel
    Rochelle Buffenstein
    Jeff Settleman
    Scientific Reports, 10
  • [10] Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein
    Deuker, Marian M.
    Lewis, Kaitlyn N.
    Ingaramo, Maria
    Kimmel, Jacob
    Buffenstein, Rochelle
    Settleman, Jeff
    SCIENTIFIC REPORTS, 2020, 10 (01)