Anemia and anemia correction: surrogate markers or causes of morbidity in chronic kidney disease?

被引：0
作者：
Nosratola D Vaziri
机构：
[1] ND Vaziri is Professor of Medicine,Physiology and Biological Science and Director of the Division of Nephrology and Hypertension at the University of California
[2] Irvine,undefined
[3] CA,undefined
[4] USA.,undefined
来源：
Nature Clinical Practice Nephrology | 2008年 / 4卷
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摘要：
In this Review, Nosratola Vaziri endeavors to reconcile two apparently conflicting sets of evidence from patients with chronic kidney disease: the observational association between greater severity of anemia and increased risk of poor outcomes, and the increased risk of adverse outcomes in patients assigned to normal, rather than subnormal, hemoglobin targets in randomized clinical trials. The author focuses on data from basic and translational studies, which are often overlooked in the design and interpretation of clinical studies and in the formulation of clinical guidelines.
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页码：436 / 445
页数：9
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