Acute pancreatitis associated with primary hyperparathyroidism

被引:14
作者
Biondi A. [1 ]
Persiani R. [2 ]
Marchese M. [2 ]
Cananzi F. [2 ]
D'Ugo D. [2 ]
机构
[1] Emergency and General Surgery Unit, Fondazione IRCCS Ca' Granda Policlinico Maggiore, 20122 Milan
[2] General Surgery Unit, Department of Surgical Sciences, Catholic University, 00168 Rome, L.go Agostino Gemelli
关键词
Acute pancreatitis; Hypercalcemia; Primary hyperparathyroidism;
D O I
10.1007/s13304-011-0048-9
中图分类号
学科分类号
摘要
Coexistence of primary hyperparathyroidism and acute pancreatitis has widely been reported in literature, but a causal relationship remains controversial. A case of acute pancreatitis as a first symptom of primary hyperparathyroidism with severe hypercalcemia is reported. In this patient a reduction of serum calcium level was obtained with medical therapy and resulted in the resolution of acute pancreatitis symptoms within 10 days. At the same time a parathyroid adenoma was clinically identified and elective parathyroidectomy was performed with complete normalization of intact parathyroid hormone and serum calcium level. At three-year follow-up, no recurrence or complications of pancreatitis were documented. The presented case suggests a cause and effect relationship between acute pancreatitis and severe hypercalcemia which should be kept in mind in the differential diagnosis of nonbiliary, non-alcoholic acute pancreatitis. Reduction of hypercalcemia with medical treatment can represent a good chance for elective surgical neck exploration. © 2011 Springer-Verlag.
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页码:135 / 138
页数:3
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