Efficient one-pot four-component synthesis of 1,4-dihydropyridines promoted by magnetite/chitosan as a magnetically recyclable heterogeneous nanocatalyst

被引：62

作者：

Maleki A. ^{[1
]}

Kamalzare M. ^{[1
]}

Aghaei M. ^{[1
]}

机构：

[1] Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran

来源：

Journal of Nanostructure in Chemistry | 2015年 / 5卷 / 1期

关键词：

1,4-dihydropyridine; Chitosan; Fe[!sub]3[!/sub]O[!sub]4[!/sub; Heterogeneous; Multicomponent reactions; Nanocatalyst;

D O I：

10.1007/s40097-014-0140-z

中图分类号：

学科分类号：

摘要：

1,4-Dihydropyridines are synthesized from various aromatic aldehyde, dimedone or 1,3-cyclohexandione, ethyl acetoacetate or methyl acetoacetate and ammonium acetate catalyzed by magnetite/chitosan at room temperature under mild reaction conditions. This process offers an easy and efficient synthesis of 1,4-dihydropyridine derivatives in high yields. The benefits of this protocol are simplicity, nontoxicity, low cost, simple work-up, and an environmentally benign nature. The catalyst is recovered by filtration and reused at least five times without significant loss in catalytic activity. © 2014, The Author(s).

引用

页码：95 / 105

页数：10

共 59 条

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