Mesenchymal stem cells-derived extracellular vesicles protect against oxidative stress-induced xenogeneic biological root injury via adaptive regulation of the PI3K/Akt/NRF2 pathway

被引:0
作者
Haojie Fu
Lin Sen
Fangqi Zhang
Sirui Liu
Meiyue Wang
Hongyan Mi
Mengzhe Liu
Bingyan Li
Shumin Peng
Zelong Hu
Jingjing Sun
Rui Li
机构
[1] The First Affiliated Hospital of Zhengzhou University,Department of Stomatology
[2] Academy of Medical Sciences at Zhengzhou University,undefined
来源
Journal of Nanobiotechnology | / 21卷
关键词
Biological tooth root; Extracellular vesicle; Oxidative stress; Extracellular matrix; Dental follicle cell;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Mesenchymal stem cells-derived extracellular vesicles protect against oxidative stress-induced xenogeneic biological root injury via adaptive regulation of the PI3K/Akt/NRF2 pathway
    Fu, Haojie
    Sen, Lin
    Zhang, Fangqi
    Liu, Sirui
    Wang, Meiyue
    Mi, Hongyan
    Liu, Mengzhe
    Li, Bingyan
    Peng, Shumin
    Hu, Zelong
    Sun, Jingjing
    Li, Rui
    JOURNAL OF NANOBIOTECHNOLOGY, 2023, 21 (01)
  • [2] Melatonin alleviates oxidative stress-induced injury to nucleus pulposus-derived mesenchymal stem cells through activating PI3K/ Akt pathway
    Huang, Ze-Nan
    Wang, Ze-Yu
    Cheng, Xiao-Fei
    Huang, Zhao-Zhang
    Han, Yan-Ling
    Cui, Ya-Zhou
    Liu, Bo
    Tian, Wei
    JOURNAL OF ORTHOPAEDIC TRANSLATION, 2023, 43 : 66 - 84
  • [3] MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system
    Wang, Tian
    Jian, Zhe
    Baskys, Andrius
    Yang, Junle
    Li, Jianying
    Guo, Hua
    Hei, Yue
    Xian, Panpan
    He, Zhongzheng
    Li, Zhengyu
    Li, Namiao
    Long, Qianfa
    BIOMATERIALS, 2020, 257 (257)
  • [4] Regulation of the Nrf2/HO-1 axis by mesenchymal stem cells-derived extracellular vesicles: implications for disease treatment
    Su, Hua
    Wang, Zhongan
    Zhou, Lidan
    Liu, Dezhi
    Zhang, Nian
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2024, 12
  • [5] Human amniotic mesenchymal stem cells-derived conditioned medium and exosomes alleviate oxidative stress-induced retinal degeneration by activating PI3K/Akt/FoxO3 pathway
    Peng, Zhe-Qing
    Guan, Xiao-Hui
    Yu, Zhen-Ping
    Wu, Jie
    Han, Xin-Hao
    Li, Ming-Hui
    Qu, Xin-Hui
    Chen, Zhi-Ping
    Han, Xiao-Jian
    Wang, Xiao-Yu
    EXPERIMENTAL EYE RESEARCH, 2024, 244
  • [6] Myricetin Protects Cells against Oxidative Stress-Induced Apoptosis via Regulation of PI3K/Akt and MAPK Signaling Pathways
    Kang, Kyoung Ah
    Wang, Zhi Hong
    Zhang, Rui
    Piao, Mei Jing
    Kim, Ki Cheon
    Kang, Sam Sik
    Kim, Young Woo
    Lee, Jongsung
    Park, Deokhoon
    Hyun, Jin Won
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2010, 11 (11): : 4348 - 4360
  • [7] New strategy of bone marrow mesenchymal stem cells against oxidative stress injury via Nrf2 pathway: oxidative stress preconditioning
    Zhang, Fei
    Peng, Wuxun
    Zhang, Jian
    Dong, Wentao
    Yuan, Dajiang
    Zheng, Yinggang
    Wang, Zhenwen
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 120 (12) : 19902 - 19914
  • [8] Spiraeoside protects human cardiomyocytes against high glucose-induced injury, oxidative stress, and apoptosis by activation of PI3K/Akt/Nrf2 pathway
    Liu, Hongyang
    Zhang, Zhiyong
    Zhang, Lei
    Yao, Xinliang
    Zhong, Xiaoming
    Cheng, Guanchang
    Wang, Lefeng
    Wan, Qilin
    JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2020, 34 (10)
  • [9] Neuroprotective mechanism of human umbilical cord mesenchymal stem cell-derived extracellular vesicles improving the phenotype polarization of microglia via the PI3K/AKT/Nrf2 pathway in vascular dementia
    Wang, Pengwei
    Yi, Tingting
    Mao, Senlin
    Li, Mingjie
    SYNAPSE, 2023, 77 (04)
  • [10] Astaxanthin Protects Retinal Photoreceptor Cells against High Glucose-Induced Oxidative Stress by Induction of Antioxidant Enzymes via the PI3K/Akt/Nrf2 Pathway
    Lai, Tso-Ting
    Yang, Chung-May
    Yang, Chang-Hao
    ANTIOXIDANTS, 2020, 9 (08) : 1 - 16