Fragment-based drug discovery takes a virtual turn

被引：0

作者：

Maurizio Pellecchia

机构：

[1] Maurizio Pellecchia is a professor of Medicinal Chemistry and Structural Biology in the Cancer Center and Infectious Diseases Center of the Burnham Institute for Medical Research,

[2] La Jolla,undefined

[3] California,undefined

[4] USA. mpellecchia@burnham.org,undefined

来源：

Nature Chemical Biology | 2009年 / 5卷

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中图分类号：

学科分类号：

摘要：

In the realm of modern drug discovery technologies, fragment-based approaches and virtual ligand screening are emerging alternative approaches to high-throughput screening (HTS). For as simple as it sounds, a hybrid approach in which fragments are discovered first in silico may be an unbeatable route to hit identification for some drug targets.

引用

页码：274 / 275

页数：1

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