Hypoxic Hepatocellular Carcinoma Cells Acquire Arsenic Trioxide Resistance by Upregulating HIF-1α Expression

被引：0
|
作者：
Yaoting Chen
Huiqing Li
Dong Chen
Xiongying Jiang
Weidong Wang
Dan Li
Hong Shan
机构：
[1] Sun Yat-sen University,Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation and Department of Interventional Radiology, Sun Yat
[2] Sun Yat-sen University,sen Memorial Hospital
[3] Sun Yat-sen University,Health Center, Sun Yat
[4] Sun Yat-sen University,sen Memorial Hospital
[5] Sun Yat-sen University,Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital
来源：
Digestive Diseases and Sciences | 2022年 / 67卷
关键词：
Hepatocellular carcinoma; Arsenic trioxide; Drug resistance; HIF-1α; Targeted therapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：3806 / 3816
页数：10
相关论文
共 50 条
  • [1] Hypoxic Hepatocellular Carcinoma Cells Acquire Arsenic Trioxide Resistance by Upregulating HIF-1α Expression
    Chen, Yaoting
    Li, Huiqing
    Chen, Dong
    Jiang, Xiongying
    Wang, Weidong
    Li, Dan
    Shan, Hong
    DIGESTIVE DISEASES AND SCIENCES, 2022, 67 (08) : 3806 - 3816
  • [2] Iron deficiency in hepatocellular carcinoma cells induced sorafenib resistance by upregulating HIF-1α to inhibit apoptosis
    Gao, Zelong
    Wang, Dongyao
    Yang, Jianxin
    Li, Min
    Ling, Changquan
    Lv, Diya
    Cao, Yan
    Chen, Zhenyu
    Shi, Ce
    Shen, Hui
    Tang, Yuxiao
    BIOMEDICINE & PHARMACOTHERAPY, 2023, 163
  • [3] Oligomycin inhibits HIF-1α expression in hypoxic tumor cells
    Gong, YQ
    Agani, FH
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2005, 288 (05): : C1023 - C1029
  • [4] Suppression of HIF-1α expression and radiation resistance in acute hypoxic conditions
    Oike, Takahiro
    Suzuki, Yoshiyuki
    Al-Jahdari, Wael
    Mobaraki, Abdulelah
    Saitoh, Jun-Ichi
    Torikai, Kohta
    Shirai, Katsuyuki
    Nakano, Takashi
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2012, 3 (01) : 141 - 145
  • [5] Periostin contributes to arsenic trioxide resistance in hepatocellular carcinoma cells under hypoxia
    Liu, Yujin
    Gao, Feng
    Song, Weixiang
    BIOMEDICINE & PHARMACOTHERAPY, 2017, 88 : 342 - 348
  • [6] Effects of arsenic trioxide on the expression of ezrin in hepatocellular carcinoma
    Lu, Wei
    Yang, Chao
    Du, Peng
    Zhang, Jun-Li
    Zhang, Jia-Cheng
    MEDICINE, 2017, 96 (35)
  • [7] Expression and clinical significance of HIF-1 a protein in hepatocellular carcinoma tissues
    丁磊
    陈孝平
    王海平
    中华肝脏病杂志, 2004, (11) : 21 - 24
  • [8] Expression and significance of MMP2 and HIF-1α in hepatocellular carcinoma
    Wang, Bin
    Ding, You-Ming
    Fan, Ping
    Wang, Bing
    Xu, Jun-Hui
    Wang, Wei-Xing
    ONCOLOGY LETTERS, 2014, 8 (02) : 539 - 546
  • [9] Arsenic Sulfide Inhibits Hepatocellular Carcinoma Metastasis by Suppressing the HIF-1α/VEGF Pathway
    Lu, Shumin
    Cai, Yu
    Kang, Ting
    Zhu, Chuanying
    Feng, Zhuowei
    Chen, Siyu
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2023, 28 (07):
  • [10] PFKFB3/HIF-1α feedback loop modulates sorafenib resistance in hepatocellular carcinoma cells
    Long, Qian
    Zou, Xuejing
    Song, Yang
    Duan, Zhijiao
    Liu, Li
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 513 (03) : 642 - 650
12345