Building the DREAM interactome

被引:0
作者
Marcos Rivas
Diego Villar
Paz González
Xosé M. Dopazo
Britt Mellstrom
José R. Naranjo
机构
[1] Consejo Superior Investigaciones Cientificas,Department of Molecular and Cellular Biology, National Center of Biotechnology
[2] Centro Investigacion Biomedica En Red de Enfermedades Neurodegenerativas-Centro Nacional de Biotecnologia,undefined
来源
Science China Life Sciences | 2011年 / 54卷
关键词
calsenilin; KChIP3; protein-protein interaction;
D O I
暂无
中图分类号
学科分类号
摘要
DREAM/calsenilin/KChIP3 is a calcium binding protein of the neuronal calcium sensor superfamily. DREAM interacts with DRE (downstream regulatory element) sites in the DNA to regulate transcription and with many proteins to exert specialized functions in different subcellular compartments. Work from different laboratories has identified a growing list of interacting proteins that constitutes the DREAM interactome. The knowledge of these interactions has greatly contributed to the understanding of the various physiological functions of DREAM.
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页码:786 / 792
页数:6
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