Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease

被引:0
作者
Ravi S. Pandey
Leah Graham
Asli Uyar
Christoph Preuss
Gareth R. Howell
Gregory W. Carter
机构
[1] The Jackson Laboratory for Genomic Medicine,Sackler School of graduate Biomedical Sciences
[2] The Jackson Laboratory,undefined
[3] Tufts University,undefined
来源
Molecular Neurodegeneration | / 14卷
关键词
Alzheimer’s disease; Animal models; Transcriptomic analysis;
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[1]  
Bettens K(2013)Genetic insights in Alzheimer's disease Lancet Neurol 12 92-104
[2]  
Sleegers K(2012)The genetics of Alzheimer disease Cold Spring Harb Perspect Med 2 a006296-964
[3]  
Van Broeckhoven C(2014)Deciphering the molecular profile of plaques, Memory Decline and Neuron Loss in Two Mouse Models for Alzheimer’s Disease by Deep Sequencing Front Aging Neurosci 6 75-551
[4]  
Tanzi RE(1984)Neurochemical characteristics of early and late onset types of Alzheimer's disease Br Med J (Clin Res Ed) 288 961-281
[5]  
Bouter Y(2013)Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s disease BMC Genomics 14 831-907
[6]  
Rossor MN(2014)The genetics of Alzheimer’s disease Clin Interv Aging 9 535-1458
[7]  
Jackson HM(2007)Genetics of Alzheimer’s Disease: A Centennial Review Neurol Clin 25 611-720
[8]  
Bagyinszky E(2010)The genetics of Alzheimer disease: Back to the future Neuron 68 270-170
[9]  
Ertekin-Taner N(1993)Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families Science 261 921-632
[10]  
Bertram L(2011)APOE and ALZHEIMER disease: a major gene with semi-dominant inheritance Mol Psychiatry 16 903-1113