The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNA

被引：0
作者：
Weijun Zhu
Rongyue Lei
Yann Le Duff
Jian Li
Fei Guo
Mark A Wainberg
Chen Liang
机构：
[1] MOH Key Laboratory of Systems Biology of Pathogens and AIDS Research Center,Departments of Medicine, Microbiology & Immunology
[2] Institute of Pathogen Biology,undefined
[3] Chinese Academy of Medical Sciences & Peking Union Medical College,undefined
[4] McGill University AIDS Centre,undefined
[5] Lady Davis Institute,undefined
[6] Jewish General Hospital,undefined
[7] McGill University,undefined
来源：
Retrovirology | / 12卷
关键词：
HIV-1; Provirus; Reservoir; CRISPR/Cas9; Genome editing;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 97 条
[1]  
Wainberg MA(2011)Development of antiretroviral drug resistance N Engl J Med 365 637-46
[2]  
Zaharatos GJ(2014)HIV infection: epidemiology, pathogenesis, treatment, and prevention Lancet 384 258-71
[3]  
Brenner BG(2012)HIV latency Cold Spring Harb Perspect Med 1 a007096-82
[4]  
Maartens G(2013)Cellular and molecular mechanisms involved in the establishment of HIV-1 latency Retrovirology 10 11-8
[5]  
Celum C(2013)Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells Nucleic Acids Res 41 7771-23
[6]  
Lewin SR(2011)A TALE nuclease architecture for efficient genome editing Nat Biotechnol 29 143-6
[7]  
Siliciano RF(2013)Multiplex genome engineering using CRISPR/Cas systems Science 339 819-12
[8]  
Greene WC(2013)RNA-guided human genome engineering via Cas9 Science 339 823-7
[9]  
Donahue DA(2007)CRISPR provides acquired resistance against viruses in prokaryotes Science 315 1709-4
[10]  
Wainberg MA(2007)The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats BMC Bioinformatics 8 172-91
12345678910