Early endometrial carcinoma: Clinicopathology, hormonal aspects, molecular genetics, diagnosis, and treatment

被引：32
作者：
Shiozawa T. [1 ]
Konishi I. [1 ]
机构：
[1] Department of Obstetrics and Gynecology, Shinshu University, School of Medicine, Matsumoto 390-8621
来源：
International Journal of Clinical Oncology | 2006年 / 11卷 / 1期
关键词：
Cell cycle; Chemotherapy; Endometrial carcinoma; Genetic alteration; Progesterone;
D O I：
10.1007/s10147-005-0546-1
中图分类号：
学科分类号：
摘要：
The number of patients with endometrial carcinoma is markedly increasing in Japan. Therefore, understanding of its biological characteristics and establishment of appropriate treatment are important. In this article, we first describe the clinicopathology of the two types of endometrial carcinoma with their hormonal background and genetic alterations, and then discuss the pathways of early endometrial carcinogenesis. In addition, we also review the diagnostic and therapeutic modalities for early endometrial carcinomas with current controversies, especially regarding postoperative treatment strategies. © The Japan Society of Clinical Oncology 2006.
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页码：13 / 21
页数：8
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