Synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones using ZrOCl2/mont K10 under microwave assisted solvent-free conditions

被引：0
作者：
B. Vijayakumar
G. Ranga Rao
机构：
[1] Indian Institute of Technology Madras,Department of Chemistry
来源：
Journal of Porous Materials | 2012年 / 19卷
关键词：
Dihydropyrimidinones/thiones; Microwave; Clay catalyst; Solvent-free; Reusable;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
ZrOCl2·8H2O supported on montmorillonite K10 (ZrOCl2/mont K10) catalyzed Biginelli reaction under solvent-free conditions is reported. The catalysts were characterized by XRD, FTIR, BET surface area analysis, and thermogravimetric analysis. The activity of montmorillonite K10, montmorillonite KSF, ZrOCl2·8H2O, SO42−/ZrO2, and ZrOCl2/mont K10s was investigated by Biginelli reaction of benzaldehyde, ethylacetoacetate and urea. The reactions were carried out by addition of ZrOCl2/mont K10 to a mixture of aldehyde, ethylacetoacetate and urea/thiourea with thorough stirring in the absence of solvent under conventional heating or microwave irradiation to prepare 3,4-dihydropyrimidin-2(1H)-one/thione derivatives at 80 °C in good yields.
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页码：491 / 497
页数：6
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